Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair.
about
A BEN-domain-containing protein associates with heterochromatin and represses transcriptionThe overexpression of MCPH1 inhibits cell growth through regulating cell cycle-related proteins and activating cytochrome c-caspase 3 signaling in cervical cancerCondensins: universal organizers of chromosomes with diverse functionsEstablishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 functionA Pocket on the Surface of the N-Terminal BRCT Domain of Mcph1 Is Required to Prevent Abnormal Chromosome CondensationDual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1Condensin suppresses recombination and regulates double-strand break processing at the repetitive ribosomal DNA array to ensure proper chromosome segregation during meiosis in budding yeast.MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathwayMcph1-deficient mice reveal a role for MCPH1 in otitis mediaPhylogeny and adaptive evolution of the brain-development gene microcephalin (MCPH1) in cetaceansHJURP interaction with the condensin II complex during G1 promotes CENP-A depositionIntegration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation.Condensin II alleviates DNA damage and is essential for tolerance of boron overload stress in Arabidopsis.BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.Submicroscopic subtelomeric aberrations in Chinese patients with unexplained developmental delay/mental retardation.Genome-wide transcriptome profiling of homologous recombination DNA repair.Primary microcephaly: do all roads lead to Rome?Primary microcephaly gene MCPH1 shows a novel molecular biomarker of human renal carcinoma and is regulated by miR-27a.Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells.A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.Primary microcephaly gene MCPH1 shows signatures of tumor suppressors and is regulated by miR-27a in oral squamous cell carcinoma.MCPH1 regulates chromosome condensation and shaping as a composite modulator of condensin II.The condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores.Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans.The centrosome and its duplication cycleSET nuclear oncogene associates with microcephalin/MCPH1 and regulates chromosome condensationArlm1 is a male-specific modifier of astrocytoma resistance on mouse Chr 12.Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment.Targeted Next-Generation Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with Hereditary Breast Cancer Susceptibility.The PHD Finger Protein MMD1/DUET Ensures the Progression of Male Meiotic Chromosome Condensation and Directly Regulates the Expression of the Condensin Gene CAP-D3.Focus on histone variant H2AX: to be or not to be.Genetic causes of microcephaly and lessons for neuronal development.Microcephalin regulates BRCA2 and Rad51-associated DNA double-strand break repair.14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response.Condensins and 3D Organization of the Interphase Nucleus.The linkage of chromatin remodeling to genome maintenance: contribution from a human disease gene BRIT1/MCPH1Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutantsMultiple roles of BRIT1/MCPH1 in DNA damage response, DNA repair, and cancer suppression.Cancer predisposing mutations in BRCT domains.
P2860
Q24337843-FD6661FE-5B3A-45C4-A9E1-B3615FCBFE8BQ24339317-B024148E-CEAC-4DE9-96F4-1B2BC9DD2E23Q24617958-5B1F0D8A-A473-4B0A-A95D-8A35AA5F695EQ27334403-C02B32B9-DA14-466D-8852-3EB96211FDB1Q27658266-7D6233A1-11F6-4C0B-8293-274C35000A52Q27671621-90AEB12F-D864-4167-91DC-AFA400F4D58FQ27939367-0116FE95-27B1-476A-925F-F7C992340E09Q28506694-BE8360D9-518F-4D68-837C-D87FDE06D24CQ28586091-C8939D47-7AB6-4F5F-87A9-C96D72F28128Q28744331-B1122BB6-D3B0-4666-A5C6-C2AF5BF10879Q30275512-0C5F8E69-6806-4C9E-B4EE-D1D6A5C13819Q30832110-EE25D310-0E87-47FA-A587-C137024F2839Q33352125-357B56B4-D8A8-456D-90BB-D4B3432D7CF2Q33527006-E0E104DE-0F87-42ED-B8C0-8A95CC2BD5D2Q33575502-3F84D6F6-22AB-4CD1-B295-64D6F041F38FQ33598112-F99ECB48-0D30-423F-9E0E-6CD3B3B1A4C9Q33629131-597DFDEA-8FB6-4A25-9B35-C6E24398A3B4Q34121413-BDEB35E2-8655-4E93-A43A-4ECEF49B611CQ34146042-96E09008-9D0A-43E8-9F72-039E78DA10C0Q34404613-DB2D5AAF-3FE3-48D9-A390-5685893FFAFAQ34614246-709153B0-903F-4A0E-AC86-FB9A3CA003E6Q34632225-9401C399-CFEA-4C7A-BC81-254BEA126176Q34663848-37D179D2-F2C0-452F-8E02-389A8290588BQ34679213-EB87ABA1-B121-47C7-BB84-074C45495DF8Q34734401-FE2E9D55-EB8C-431E-BEF4-6053ABCC53B9Q35045117-8BF30FBB-FC2E-4664-AE0D-D067C083D0DDQ35065191-6C1EB336-B7C1-4266-A88D-5CCD04EDD974Q35696405-2EF84274-7AA9-4032-964D-A7A302AD69F1Q35838961-22487143-2232-4B72-A23A-45DE826DB2F5Q35906993-38071B82-913A-426D-8D3B-6DB92EB50D00Q36069401-0CF927C4-ABBD-49DE-8507-98AB365DF1C5Q36963162-9B27F492-5CEA-4AB0-851F-BDF0EDD61220Q37158051-5720347D-D261-45A4-8CE7-5DF62467AE78Q37253346-8362C473-E374-4BFA-AD8B-F38888BCC45EQ37501480-431D9B2F-A6B0-45E1-B802-8FF23298E5BDQ37590878-0A51719C-D985-4FBF-BC20-23DF3CFA0477Q37614824-80D9EE73-E431-49D9-B84F-6174AEF793C7Q37696358-C309D1CE-E89A-4995-9F3B-5668B66B27FFQ37727114-3A1370B9-3215-4E05-9C4E-2478ACCEB59DQ37893590-A473D775-E2FF-4DEE-881A-D07C78212AC5
P2860
Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Microcephalin/MCPH1 associates ...... mologous recombination repair.
@en
Microcephalin/MCPH1 associates ...... mologous recombination repair.
@nl
type
label
Microcephalin/MCPH1 associates ...... mologous recombination repair.
@en
Microcephalin/MCPH1 associates ...... mologous recombination repair.
@nl
prefLabel
Microcephalin/MCPH1 associates ...... mologous recombination repair.
@en
Microcephalin/MCPH1 associates ...... mologous recombination repair.
@nl
P2093
P2860
P356
P1476
Microcephalin/MCPH1 associates ...... omologous recombination repair
@en
P2093
Jamie L Wood
Junjie Chen
P2860
P304
29586-29592
P356
10.1074/JBC.M804080200
P407
P50
P577
2008-08-21T00:00:00Z