Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling. - Wikidata - awgldk - TriplyDB

Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling.

Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling.

http://www.wikidata.org/entity/Q39949529

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Immunosuppressive Mechanisms of Malignant Gliomas: Parallels at Non-CNS Sites Twisted tango: brain tumor neurovascular interactions TGF-β signaling and its targeting for glioma treatment Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis TGF-beta1 blockade of microglial chemotaxis toward Abeta aggregates involves SMAD signaling and down-regulation of CCL5 Comparison of the gene expression profiles of human fetal cortical astrocytes with pluripotent stem cell derived neural stem cells identifies human astrocyte markers and signaling pathways and transcription factors active in human astrocytes Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodies.Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin αvβ3 The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma.IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction.The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.Shape matters: intravital microscopy reveals surprising geometrical dependence for nanoparticles in tumor models of extravasation.Tissue and serum IGFBP7 protein as biomarker in high-grade soft tissue sarcoma Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.Biodegradable Mg-Cu alloys with enhanced osteogenesis, angiogenesis, and long-lasting antibacterial effects.Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay Epithelial ovarian cancer-induced angiogenic phenotype of human omental microvascular endothelial cells may occur independently of VEGF signaling.Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype.Metastatic biomarkers in synovial sarcoma.Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment.The glioblastoma vasculature as a target for cancer therapy.Neural Regulation of CNS Angiogenesis During Development.Transforming growth factor β and bone morphogenetic protein actions in brain tumors.Interleukin-1-induced changes in the glioblastoma secretome suggest its role in tumor progression.PVT1 affects growth of glioma microvascular endothelial cells by negatively regulating miR-186.Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium.High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-β and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner.Insulin-like growth factor binding protein 7 modulates estrogen-induced trophoblast proliferation and invasion in HTR-8 and JEG-3 cells.Down-regulation of Connexin43 expression reveals the involvement of caveolin-1 containing lipid rafts in human U251 glioblastoma cell invasion.Microarray analysis in a cell death resistant glioma cell line to identify signaling pathways and novel genes controlling resistance and malignancy.Insulin-like growth factor binding protein 7 and tissue inhibitor of metalloproteinases-2: differential expression and secretion in human kidney tubule cells.GBM secretome induces transient transformation of human neural precursor cells.Secretome analysis of in vitro aged human mesenchymal stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis.IGFBP7's susceptibility to proteolysis is altered by A-to-I RNA editing of its transcript.Proteomic analysis of hypoxia-induced U373MG glioma secretome reveals novel hypoxia-dependent migration factors.Function and expression of insulin-like growth factor-binding protein 7 (IGFBP7) gene in childhood acute myeloid leukemia.

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Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling.

http://www.wikidata.org/entity/Q39949529

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Glioblastoma-secreted factors ...... -dependent TGF-beta signaling.

@en

Glioblastoma-secreted factors ...... -dependent TGF-beta signaling.

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type

label

Glioblastoma-secreted factors ...... -dependent TGF-beta signaling.

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Glioblastoma-secreted factors ...... -dependent TGF-beta signaling.

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prefLabel

Glioblastoma-secreted factors ...... -dependent TGF-beta signaling.

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Glioblastoma-secreted factors ...... -dependent TGF-beta signaling.

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Glioblastoma-secreted factors ...... -dependent TGF-beta signaling.

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A Pen

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D B Stanimirovic

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M J Moreno

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TGF-beta signal transduction

Genes expressed in human tumor endothelium

Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II

Cell adhesion activity of a 30-kDa major secreted protein from human bladder carcinoma cells

Purification and molecular cloning of prostacyclin-stimulating factor from serum-free conditioned medium of human diploid fibroblast cells

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

Identification of another member of the transforming growth factor type beta gene family

A simple salting out procedure for extracting DNA from human nucleated cells

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10.1038/ONC.2008.287

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