Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer.
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CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genesChromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomasRole of CHD5 in human cancers: 10 years laterSyntenic relationships between genomic profiles of fiber-induced murine and human malignant mesotheliomaCHD5 is required for spermiogenesis and chromatin condensationChd5 requires PHD-mediated histone 3 binding for tumor suppressionArray-based DNA methylation profiling of primary lymphomas of the central nervous system.The tumor suppressor chromodomain helicase DNA-binding protein 5 (CHD5) remodels nucleosomes by unwrapping.MicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5Multivalent recognition of histone tails by the PHD fingers of CHD5Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromesTherapeutic targets for neuroblastomas.Genetics, cytogenetics, and epigenetics of colorectal cancer.The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.The tumour suppressor CHD5 forms a NuRD-type chromatin remodelling complex.Mechanisms of CHD5 Inactivation in neuroblastomas.Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancerMutual regulation between CHD5 and EZH2 in hepatocellular carcinoma.Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas.Long non-coding RNAs and their implications in cancer epigenetics.Decreased expression of the CHD5 gene and its clinicopathological significance in breast cancer: Correlation with aberrant DNA methylation.Silencing of CHD5 gene by promoter methylation in leukemia.Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages.Apoptotic cell death in neuroblastoma.The Chromodomain Helicase DNA-Binding Chromatin Remodelers: Family Traits that Protect from and Promote Cancer.Chromatin as an oxygen sensor and active player in the hypoxia response.Drosophila cancer models.Chromatin regulators with tumor suppressor properties and their alterations in human cancers.Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma.The tumor suppressor Chd5 is induced during neuronal differentiation in the developing mouse brain.CHD5 is down-regulated through promoter hypermethylation in gastric cancer.Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.Decreased expression of chromodomain helicase DNA-binding protein 5 is an unfavorable prognostic marker in patients with primary gallbladder carcinoma.Histone deacetylase 3 is associated with gastric cancer cell growth via the miR-454-mediated targeting of CHD5.CTCF-KDM4A complex correlates with histone modifications that negatively regulate CHD5 gene expression in cancer cell lines.Targeting the epigenome for treatment of cancer.CHD5 a tumour suppressor is epigenetically silenced in hepatocellular carcinoma.
P2860
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P2860
Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Chromatin remodeling factor CH ...... ermethylation in human cancer.
@en
Chromatin remodeling factor CH ...... ermethylation in human cancer.
@nl
type
label
Chromatin remodeling factor CH ...... ermethylation in human cancer.
@en
Chromatin remodeling factor CH ...... ermethylation in human cancer.
@nl
prefLabel
Chromatin remodeling factor CH ...... ermethylation in human cancer.
@en
Chromatin remodeling factor CH ...... ermethylation in human cancer.
@nl
P356
P1433
P1476
Chromatin remodeling factor CH ...... ermethylation in human cancer.
@en
P2093
Sonia Mulero-Navarro
P304
P356
10.4161/EPI.3.4.6610
P577
2008-07-16T00:00:00Z