Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11.

Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11.

Item
http://www.wikidata.org/entity/Q39966104
Multiple Drug Transport Pathways through Human P-Glycoprotein.Intragenic suppressing mutations correct the folding and intracellular traffic of misfolded mutants of Yor1p, a eukaryotic drug transporter.Human P-glycoprotein contains a greasy ball-and-socket joint at the second transmission interface.What can naturally occurring mutations tell us about Ca(v)1.x channel function?Identification of the distance between the homologous halves of P-glycoprotein that triggers the high/low ATPase activity switch.Identification of residues in the drug translocation pathway of the human multidrug resistance P-glycoprotein by arginine mutagenesisLocking intracellular helices 2 and 3 together inactivates human P-glycoprotein.Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1)A promiscuous conformational switch in the secondary multidrug transporter MdfA.Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania.Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoprotein.Targeted Next-Generation Sequencing for Comprehensive Genetic Profiling of Pharmacogenes.Position 834 in TM6 plays an important role in cholesterol and phosphatidylcholine transport by ABCA1.
P2860

Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11.

Item
http://www.wikidata.org/entity/Q39966104
description
2008 nî lūn-bûn
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2008年の論文
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Arginines in the first transme ...... s in transmembrane segment 11.
@en
Arginines in the first transme ...... s in transmembrane segment 11.
@nl
type
label
Arginines in the first transme ...... s in transmembrane segment 11.
@en
Arginines in the first transme ...... s in transmembrane segment 11.
@nl
prefLabel
Arginines in the first transme ...... s in transmembrane segment 11.
@en
Arginines in the first transme ...... s in transmembrane segment 11.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Arginines in the first transme ...... s in transmembrane segment 11.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932