Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoprotein.
about
Drug-protein hydrogen bonds govern the inhibition of the ATP hydrolysis of the multidrug transporter P-glycoproteinThiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1.Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site.Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions.Structure-function relationships in ABCG2: insights from molecular dynamics simulations and molecular docking studies.Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency.Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast
P2860
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P2860
Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoprotein.
description
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name
Mapping the Binding Site of th ...... rane Domain of P-glycoprotein.
@en
Mapping the Binding Site of th ...... rane Domain of P-glycoprotein.
@nl
type
label
Mapping the Binding Site of th ...... rane Domain of P-glycoprotein.
@en
Mapping the Binding Site of th ...... rane Domain of P-glycoprotein.
@nl
prefLabel
Mapping the Binding Site of th ...... rane Domain of P-glycoprotein.
@en
Mapping the Binding Site of th ...... rane Domain of P-glycoprotein.
@nl
P2860
P356
P1476
Mapping the Binding Site of th ...... brane Domain of P-glycoprotein
@en
P2093
David M Clarke
P2860
P304
29389-29401
P356
10.1074/JBC.M115.695171
P407
P577
2015-10-26T00:00:00Z