Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
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Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effectorItraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonistsArsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancerBIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cellsCurcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt DegradationArsenic trioxide inhibits tumor-induced myeloid-derived suppressor cells and enhances T-cell activity.Influence of arsenate and arsenite on signal transduction pathways: an updateMutant p53 protein is targeted by arsenic for degradation and plays a role in arsenic-mediated growth suppression.Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.Arsenic trioxide-induced growth arrest of breast cancer MCF-7 cells involving FOXO3a and IκB kinase β expression and localization.Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein.Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol.Fucoidan enhances the therapeutic potential of arsenic trioxide and all-trans retinoic acid in acute promyelocytic leukemia, in vitro and in vivo.The evolving use of arsenic in pharmacotherapy of malignant disease.13-Oxyingenol dodecanoate, a cytotoxic ingenol derivative, induces mitochondrial apoptosis and caspase-dependent Akt decrease in K562 cells.Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.Arsenite causes down-regulation of Akt and c-Fos, cell cycle dysfunction and apoptosis in glutathione-deficient cells.Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells.Arsenic trioxide potentiates the anti-cancer activities of sorafenib against hepatocellular carcinoma by inhibiting Akt activation.PI3K/Akt/mTOR Signaling Pathway and the Biphasic Effect of Arsenic in Carcinogenesis.
P2860
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P2860
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
@en
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
@nl
type
label
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
@en
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
@nl
prefLabel
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
@en
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
@nl
P2093
P1476
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
@en
P2093
Koren K Mann
Myrian Colombo
Wilson H Miller
P304
P356
10.1158/1535-7163.MCT-07-2164
P577
2008-06-01T00:00:00Z