HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression.
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Molecular mechanisms involved in farnesol-induced apoptosisInflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologiesHepatic Fgf21 Expression Is Repressed after Simvastatin Treatment in MiceSimvastatin decreases endothelial progenitor cell apoptosis in the kidney of hypertensive hypercholesterolemic pigsThe role of endoplasmic reticulum stress in the progression of atherosclerosis.Chikusetsu saponin V attenuates MPP+-induced neurotoxicity in SH-SY5Y cells via regulation of Sirt1/Mn-SOD and GRP78/caspase-12 pathways.Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2.Atorvastatin ameliorates myocardial ischemia/reperfusion injury through attenuation of endoplasmic reticulum stress-induced apoptosis.A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycinHydrogen sulfide inhibits formaldehyde-induced endoplasmic reticulum stress in PC12 cells by upregulation of SIRT-1.Atorvastatin inhibits myocardial cell apoptosis in a rat model with post-myocardial infarction heart failure by downregulating ER stress response.Lipidome and transcriptome profiling of pneumolysin intoxication identifies networks involved in statin-conferred protection of airway epithelial cells.Atorvastatin up-regulates TRIB3 independent of ATF4-CHOP pathway in atherosclerotic patients.Statin-conferred enhanced cellular resistance against bacterial pore-forming toxins in airway epithelial cellsElimination of endoplasmic reticulum stress and cardiovascular, type 2 diabetic, and other metabolic diseases.Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondriaStatins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans.Cell biology of ischemia/reperfusion injury.Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth.Proteomic analysis of lipid raft-enriched membranes isolated from internal organelles.HER2-mTOR signaling-driven breast cancer cells require ER-associated degradation to survive.The anti-obesity drug orlistat reveals anti-viral activity.Ischemia/Reperfusion.Statins reduce dengue virus production via decreased virion assembly.Disturbance of hippocampal H2S generation contributes to CUMS-induced depression-like behavior: involvement in endoplasmic reticulum stress of hippocampus.Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells.Neuroprotective effects of atorvastatin against cerebral ischemia/reperfusion injury through the inhibition of endoplasmic reticulum stress.Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts.Atorvastatin inhibits CD68 expression in aortic root through a GRP78-involved pathway.Inhibitory Effects of Simvastatin on Oxidized Low-Density Lipoprotein-Induced Endoplasmic Reticulum Stress and Apoptosis in Vascular Endothelial Cells.
P2860
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P2860
HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
HMG-CoA reductase inhibitors a ...... toprotective GRP78 expression.
@en
HMG-CoA reductase inhibitors a ...... toprotective GRP78 expression.
@nl
type
label
HMG-CoA reductase inhibitors a ...... toprotective GRP78 expression.
@en
HMG-CoA reductase inhibitors a ...... toprotective GRP78 expression.
@nl
prefLabel
HMG-CoA reductase inhibitors a ...... toprotective GRP78 expression.
@en
HMG-CoA reductase inhibitors a ...... toprotective GRP78 expression.
@nl
P2860
P356
P1476
HMG-CoA reductase inhibitors a ...... ytoprotective GRP78 expression
@en
P2093
Jui-Ching Chen
Mei-Lin Wu
P2860
P304
P356
10.1093/CVR/CVN160
P577
2008-06-12T00:00:00Z