A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation
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Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon RegenerationLipid biology of breast cancerAnaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cellsNerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to EpacIdentification of a novel TGFβ/PKA signaling transduceome in mediating control of cell survival and metastasis in colon cancer.AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier propertiesHepatocyte proliferation during liver regeneration is impaired in mice with methionine diet-induced hyperhomocysteinemia.Switch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines.Grb-2-associated binder 1 (Gab1) regulates postnatal ischemic and VEGF-induced angiogenesis through the protein kinase A-endothelial NOS pathway.Dissecting molecular events in thyroid neoplasia provides evidence for distinct evolution of follicular thyroid adenoma and carcinomaNeuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity.cAMP signaling increases histone deacetylase 8 expression via the Epac2-Rap1A-Akt pathway in H1299 lung cancer cells.cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac.Dual TORCs driven and B56 orchestrated signaling network guides eukaryotic cell migration.PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-kappaB-independent manner.The Role of Protein Kinase B Signaling Pathway in Anti-Cancer Effect of Rolipram on Glioblastoma Multiforme: An In Vitro Study.Olprinone and colforsin daropate alleviate septic lung inflammation and apoptosis through CREB-independent activation of the Akt pathway.Relative importance of phosphatidylinositol-3 kinase (PI3K)/Akt and mitogen-activated protein kinase (MAPK3/1) signaling during maturational steroid-induced meiotic G2-M1 transition in zebrafish oocytes.Phosphatidic acid induces decidualization by stimulating Akt-PP2A binding in human endometrial stromal cells.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Cooperation of Epac1/Rap1/Akt and PKA in prostaglandin E(2) -induced proliferation of human umbilical cord blood derived mesenchymal stem cells: involvement of c-Myc and VEGF expression.
P2860
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P2860
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
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name
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation
@en
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation.
@nl
type
label
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation
@en
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation.
@nl
prefLabel
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation
@en
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation.
@nl
P2093
P2860
P356
P1476
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation
@en
P2093
Daniel L Altschuler
Fernando Ribeiro-Neto
Kyoungja Hong
Liguang Lou
Sandhya Gupta
P2860
P304
23129-23138
P356
10.1074/JBC.M800478200
P407
P577
2008-06-12T00:00:00Z