Mechanisms involved in the reduction of GABAA receptor alpha1-subunit expression caused by the epilepsy mutation A322D in the trafficking-competent receptor.
about
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyThe developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy.GABA(A) receptor alpha1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABA(A) receptorsmRNA surveillance and endoplasmic reticulum quality control processes alter biogenesis of mutant GABAA receptor subunits associated with genetic epilepsies.A de novo missense mutation of GABRB2 causes early myoclonic encephalopathyCombining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated γ-aminobutyric acid, type A (GABAA) receptorsGABAA receptor trafficking-mediated plasticity of inhibitory synapses.Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA.Agonist-dependent endocytosis of γ-aminobutyric acid type A (GABAA) receptors revealed by a γ2(R43Q) epilepsy mutation.Conduits of life's spark: a perspective on ion channel research since the birth of neuron.Dynamin- and lipid raft-dependent entry of decay-accelerating factor (DAF)-binding and non-DAF-binding coxsackieviruses into nonpolarized cellsSAHA enhances Proteostasis of epilepsy-associated α1(A322D)β2γ2 GABA(A) receptors.Allosteric modulation of GABAA receptors by extracellular ATP.Mutations in GABAA receptor subunits associated with genetic epilepsies.Calnexin improves the folding efficiency of mutant rhodopsin in the presence of pharmacological chaperone 11-cis-retinal.Molecular pathology of genetic epilepsies associated with GABAA receptor subunit mutations.GABA type a receptor trafficking and the architecture of synaptic inhibition.Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.
P2860
Q27015793-5697229B-9E2B-4D0B-B2B0-2B2D99C051DEQ27308026-CAED0336-657C-43CD-933E-05090B8B9F1DQ34074424-D73F18CE-824F-4ACE-B92E-1BA850C61DA6Q34315858-A5AA6425-5C07-4885-AEC9-9030630CB94DQ34543571-B3509731-A2FB-4E50-AF1A-D74EE41AA2A6Q34801457-9B534835-2A9E-41A5-9EB1-499B7B19D5B0Q34979365-998CD542-270F-48AB-B591-CF06EF938F35Q35617513-A87E88B5-DB02-426C-8A5E-F3489AEDE2CBQ37201295-39AE6761-D3DB-4763-92C0-DE1794E9C18AQ37401733-31C542CA-B6E3-4046-8BD7-7B332F878B64Q37410850-F9252FB5-0AFE-4C82-9D40-FEB7FB482CB6Q37412871-D1E5B035-9250-4CF8-BDE1-3D6E1A970861Q37523445-8D1111F7-8E67-4822-8A06-37DC8A5953DFQ37716303-221AB434-1169-48FB-A913-AFCED386A4E2Q39791822-ECC28F47-1725-4ADA-98C1-BDDEF59B1301Q43146745-EEAD4F8B-D2AA-4029-B119-B4810C209052Q47810846-025D5506-84F8-4C8A-B329-028717B7FACCQ47967839-FDD0E565-65AF-4511-96FA-463943706A6D
P2860
Mechanisms involved in the reduction of GABAA receptor alpha1-subunit expression caused by the epilepsy mutation A322D in the trafficking-competent receptor.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Mechanisms involved in the red ...... rafficking-competent receptor.
@en
Mechanisms involved in the red ...... rafficking-competent receptor.
@nl
type
label
Mechanisms involved in the red ...... rafficking-competent receptor.
@en
Mechanisms involved in the red ...... rafficking-competent receptor.
@nl
prefLabel
Mechanisms involved in the red ...... rafficking-competent receptor.
@en
Mechanisms involved in the red ...... rafficking-competent receptor.
@nl
P2093
P2860
P356
P1476
Mechanisms involved in the red ...... rafficking-competent receptor.
@en
P2093
Changiz Taghibiglou
Clarrisa A Bradley
Graham L Collingridge
Yu Tian Wang
P2860
P304
22043-22050
P356
10.1074/JBC.M801708200
P407
P577
2008-06-05T00:00:00Z