Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyl transferase deficiency. Clinical, biochemical, pharmacologic and genetic evidence for heterogeneity.
about
Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cellsCloning of a human liver microsomal UDP-glucuronosyltransferase cDNAPharmGKB summary: very important pharmacogene information for UGT1A1Inherited disorders of bilirubin clearanceGenetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotypeSpectrum of UGT1A1 Variations in Chinese Patients with Crigler-Najjar Syndrome Type IIChromosomal assignment of human phenol and bilirubin UDP-glucuronosyltransferase genes (UGT1A-subfamily)Genes for jaundice.Stimulation of bilirubin catabolism in jaundiced Gunn rats by an induced of microsomal mixed-function monooxygenasesBilirubin uridine diphosphate-glucuronosyltransferase variation is a genetic basis of breast milk jaundice.Identification of two single base substitutions in the UGT1 gene locus which abolish bilirubin uridine diphosphate glucuronosyltransferase activity in vitro.Pharmacogenomics: a systems approach.N-acetylation and debrisoquine hydroxylation polymorphisms in patients with Gilbert's syndrome.Splice-site mutations: a novel genetic mechanism of Crigler-Najjar syndrome type 1.New insights into the classification and mechanisms of hereditary, chronic, non-haemolytic hyperbilirubinaemias.Role of bilirubin overproduction in revealing Gilbert's syndrome: is dyserythropoiesis an important factor?Inheritance of type 2 Crigler-Najjar hyperbilirubinaemiaGenetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation.Comparison of treatments for congenital nonobstructive nonhaemolytic hyperbilirubinaemia.Long term phototherapy in Crigler-Najjar syndromeCosegregation of intragenic markers with a novel mutation that causes Crigler-Najjar syndrome type I: implication in carrier detection and prenatal diagnosisIdentification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient.Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase.Needs for animal models of human diseases of the gastrointestinal systemRole of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced neonatal hyperbilirubinemia.Characterization of the major diazo-positive pigments in bile of homozygous Gunn rats.Familial intrahepatic cholestasis: an updateHepatic conversion of bilirubin monoglucuronide to diglucuronide in uridine diphosphate-glucuronyl transferase-deficient man and rat by bilirubin glucuronoside glucuronosyltransferase.Gene therapy for liver enzyme deficiencies: what have we learned from models for Crigler-Najjar and tyrosinemia?Contributions of the Ah receptor to bilirubin homeostasis and its antioxidative and atheroprotective functions.Bile acid receptors as targets for drug development.Gene replacement therapy for genetic hepatocellular jaundice.Role and nature of plasma membrane carrier proteins in the hepatic transport of organic anions.Truncated UDP-glucuronosyltransferase (UGT) from a Crigler-Najjar syndrome type II patient colocalizes with intact UGT in the endoplasmic reticulum.Prenatal diagnosis of Crigler-Najjar syndrome type I by single-strand conformation polymorphism (SSCP).The molecular basis of jaundice: An old symptom revisited.Postnatal development of uridine diphosphate glucuronyltransferase activity towards bilirubin and 2-aminophenol in human liver.Effects of environmental chemicals on the metabolism of drugs, carcinogens, and normal body constituents in man.Human cytochromes P-450.Bilirubin excretion in rats with normal and impaired bilirubin conjugation: effect of phenobarbital.
P2860
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P2860
Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyl transferase deficiency. Clinical, biochemical, pharmacologic and genetic evidence for heterogeneity.
description
1969 nî lūn-bûn
@nan
1969年の論文
@ja
1969年学术文章
@wuu
1969年学术文章
@zh-cn
1969年学术文章
@zh-hans
1969年学术文章
@zh-my
1969年学术文章
@zh-sg
1969年學術文章
@yue
1969年學術文章
@zh
1969年學術文章
@zh-hant
name
Chronic nonhemolytic unconjuga ...... ic evidence for heterogeneity.
@en
Chronic nonhemolytic unconjuga ...... ic evidence for heterogeneity.
@nl
type
label
Chronic nonhemolytic unconjuga ...... ic evidence for heterogeneity.
@en
Chronic nonhemolytic unconjuga ...... ic evidence for heterogeneity.
@nl
prefLabel
Chronic nonhemolytic unconjuga ...... ic evidence for heterogeneity.
@en
Chronic nonhemolytic unconjuga ...... ic evidence for heterogeneity.
@nl
P2093
P1476
Chronic nonhemolytic unconjuga ...... ic evidence for heterogeneity.
@en
P2093
P304
P356
10.1016/0002-9343(69)90224-1
P407
P577
1969-09-01T00:00:00Z