Thiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4 - Wikidata - awgldk - TriplyDB

Thiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4

Thiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4

http://www.wikidata.org/entity/Q39990304

about

Structural insights into ribosome translocation Thiopeptide antibiotics: retrospective and recent advances Invariom refinement of a new monoclinic solvate of thiostrepton at 0.64 Å resolution The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome New antimycobacterial agents in the pre-clinical phase or beyond: recent advances in patent literature (2001-2016).Common chaperone activity in the G-domain of trGTPase protects L11-L12 interaction on the ribosome Principal component and clustering analysis on molecular dynamics data of the ribosomal L11·23S subdomain The antituberculosis antibiotic capreomycin inhibits protein synthesis by disrupting interaction between ribosomal proteins L12 and L10.The bacterial translation stress response.Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system.Conformational changes of elongation factor G on the ribosome during tRNA translocation Functional roles in S-adenosyl-L-methionine binding and catalysis for active site residues of the thiostrepton resistance methyltransferase Identification of antituberculosis agents that target ribosomal protein interactions using a yeast two-hybrid system.Elongation factor 4 remodels the A-site tRNA on the ribosome The paradox of elongation factor 4: highly conserved, yet of no physiological significance?YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.A brief history of antibiotics and select advances in their synthesis.Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams.Identification of two structural elements important for ribosome-dependent GTPase activity of elongation factor 4 (EF4/LepA).Ribosomal protein L7/L12 is required for GTPase translation factors EF-G, RF3, and IF2 to bind in their GTP state to 70S ribosomes.Identification of Agents Active against Methicillin-Resistant Staphylococcus aureus USA300 from a Clinical Compound Library.Characterization of a novel plasmid-borne thiopeptide gene cluster in Staphylococcus epidermidis strain 115.The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics.

P2860

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P2860

Thiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4

http://www.wikidata.org/entity/Q39990304

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

2011年學術文章

@zh

2011年學術文章

@zh-hant

name

Thiostrepton inhibits stable 7 ...... ctor G and elongation factor 4

@en

Thiostrepton inhibits stable 7 ...... tor G and elongation factor 4.

@nl

type

label

Thiostrepton inhibits stable 7 ...... ctor G and elongation factor 4

@en

Thiostrepton inhibits stable 7 ...... tor G and elongation factor 4.

@nl

prefLabel

Thiostrepton inhibits stable 7 ...... ctor G and elongation factor 4

@en

Thiostrepton inhibits stable 7 ...... tor G and elongation factor 4.

@nl

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P1433

Nucleic Acids Research

P1476

Thiostrepton inhibits stable 7 ...... ctor G and elongation factor 4

@en

P2093

Geoff Traeger

http://www.w3.org/2001/XMLSchema#string

Justin D Walter

http://www.w3.org/2001/XMLSchema#string

Margaret Hunter

http://www.w3.org/2001/XMLSchema#string

Melanie Cobb

http://www.w3.org/2001/XMLSchema#string

P Clint Spiegel

http://www.w3.org/2001/XMLSchema#string

P2860

Structures of the bacterial ribosome in classical and hybrid states of tRNA binding

The structure of LepA, the ribosomal back translocase

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit

The structures of four macrolide antibiotics bound to the large ribosomal subunit

L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy

Structural basis for contrasting activities of ribosome binding thiazole antibiotics

Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit.

Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin

Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

P304

360-370

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scholarly article

P356

10.1093/NAR/GKR623

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1

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40

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2011-09-09T00:00:00Z

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51639859

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21908407

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3245911

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