Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification. - Wikidata - awgldk - TriplyDB

Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification.

Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification.

http://www.wikidata.org/entity/Q39991815

about

An overview of epigenetics and chemoprevention Implications of Genetic and Epigenetic Alterations of CDKN2A (p16(INK4a)) in Cancer Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics Environmental epigenetics and phytoestrogen/phytochemical exposures Epigenetic diet: impact on the epigenome and cancer Therapeutic targeting of replicative immortality Environmental epigenetics and its implication on disease risk and health outcomes Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.Bidirectional transcription directs both transcriptional gene activation and suppression in human cells Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene.Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components.Epigenetic modifications by dietary phytochemicals: implications for personalized nutrition MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer.Regulation of the human catalytic subunit of telomerase (hTERT).Top associated SNPs in prostate cancer are significantly enriched in cis-expression quantitative trait loci and at transcription factor binding sites.Genistein cooperates with the histone deacetylase inhibitor vorinostat to induce cell death in prostate cancer cells.Cancer chemoprevention by dietary polyphenols: promising role for epigenetics.Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications Genistein affects histone modifications on Dickkopf-related protein 1 (DKK1) gene in SW480 human colon cancer cell line.Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms.Impact of soy isoflavones on the epigenome in cancer prevention.Epigenetic targets of bioactive dietary components for cancer prevention and therapy.Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells.A novel prodrug of epigallocatechin-3-gallate: differential epigenetic hTERT repression in human breast cancer cells.p53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia.Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR.Role of diet in prostate cancer: the epigenetic link.Epigenetic alterations in ultraviolet radiation-induced skin carcinogenesis: interaction of bioactive dietary components on epigenetic targets Sulforaphane induction of p21(Cip1) cyclin-dependent kinase inhibitor expression requires p53 and Sp1 transcription factors and is p53-dependent.Targeting the epigenome with bioactive food components for cancer prevention Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators.Natural products as potential cancer therapy enhancers: A preclinical update.Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer.Screening and identification of glyceollins and their metabolites by electrospray ionization tandem mass spectrometry with precursor ion scanning.Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression.DNA methylation and histone modifications of Wnt genes by genistein during colon cancer development.Soy Isoflavone Genistein-Mediated Downregulation of miR-155 Contributes to the Anticancer Effects of Genistein.

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P2860

Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification.

http://www.wikidata.org/entity/Q39991815

description

2008 nî lūn-bûn

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2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

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2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Genistein induces the p21WAF1/ ...... active chromatin modification.

@en

Genistein induces the p21WAF1/ ...... active chromatin modification.

@nl

type

label

Genistein induces the p21WAF1/ ...... active chromatin modification.

@en

Genistein induces the p21WAF1/ ...... active chromatin modification.

@nl

prefLabel

Genistein induces the p21WAF1/ ...... active chromatin modification.

@en

Genistein induces the p21WAF1/ ...... active chromatin modification.

@nl

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0008-5472.CAN-07-2290

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Cancer Research

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Genistein induces the p21WAF1/ ...... active chromatin modification.

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P2093

Deepa Pookot

http://www.w3.org/2001/XMLSchema#string

Emily Noonan

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Hiroshi Hirata

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Hong Zhao

http://www.w3.org/2001/XMLSchema#string

Jason Nelles

http://www.w3.org/2001/XMLSchema#string

Ken Kawamoto

http://www.w3.org/2001/XMLSchema#string

Long C Li

http://www.w3.org/2001/XMLSchema#string

Nobuyuki Kikuno

http://www.w3.org/2001/XMLSchema#string

Rajvir Dahiya

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Robert F Place

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2736-2744

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scholarly article

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10.1158/0008-5472.CAN-07-2290

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8

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68

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2008-04-01T00:00:00Z

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18413741

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