Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl- transport in biliary epithelial cells through a PKCzeta-dependent pathway.
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Purinergic signalling in the gastrointestinal tract and related organs in health and diseasePhysiology of cholangiocytesCholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptorsMechanical stimulation evokes rapid increases in extracellular adenosine concentration in the prefrontal cortex.Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor toneTwo distinct phases of calcium signalling under flow.5-Nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) stimulates cellular ATP release through exocytosis of ATP-enriched vesiclesSpatially resolved shear distribution in microfluidic chip for studying force transduction mechanisms in cells.Initiation of purinergic signaling by exocytosis of ATP-containing vesicles in liver epitheliumAdenosine triphosphate release and purinergic (P2) receptor-mediated secretion in small and large mouse cholangiocytes.Adrenergic receptor activation involves ATP release and feedback through purinergic receptors.Endogenous luminal surface adenosine signaling regulates duodenal bicarbonate secretion in ratsIdentification and functional characterization of TMEM16A, a Ca2+-activated Cl- channel activated by extracellular nucleotides, in biliary epithelium.Coupled ATP and potassium efflux from intercalated cells.Regulation of purinergic signaling in biliary epithelial cells by exocytosis of SLC17A9-dependent ATP-enriched vesicles.Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growthNormal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics.Role of purinergic P2X receptors in the control of liver homeostasis.Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6PKCα regulates TMEM16A-mediated Cl⁻ secretion in human biliary cellsMechanosensitive Cl- secretion in biliary epithelium mediated through TMEM16A.Regulation of mechanosensitive biliary epithelial transport by the epithelial Na(+) channel.Extracellular nucleotides stimulate Cl- currents in biliary epithelia through receptor-mediated IP3 and Ca2+ releaseAttenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cellsRole of BK channels in hypertension and potassium secretion.Identification and functional characterization of the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) in biliary epithelium.Purinergic signalling in epithelial ion transport: regulation of secretion and absorption.Human hepatic stem cell and maturational liver lineage biology.Molecular targets for the treatment of fibrosing cholangiopathies.Adenylyl cyclases in the digestive system.Calcium signaling and the secretory activity of bile duct epithelia.Cystic fibrosis: an update for clinicians. Part 2: hepatobiliary and pancreatic manifestations.Cell culture: complications due to mechanical release of ATP and activation of purinoceptors.ATP release, generation and hydrolysis in exocrine pancreatic duct cells.Multiscale computational model of fluid flow and matrix deformation in decellularized liver.Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts.Pathobiology of biliary epithelia.Compensatory role of inducible annexin A2 for impaired biliary epithelial anion-exchange activity of inflammatory cholangiopathy.AVP-stimulated nucleotide secretion in perfused mouse medullary thick ascending limb and cortical collecting duct.Extracellular ATP inhibits chloride channels in mature mammalian skeletal muscle by activating P2Y1 receptors.
P2860
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P2860
Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl- transport in biliary epithelial cells through a PKCzeta-dependent pathway.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Fluid flow induces mechanosens ...... h a PKCzeta-dependent pathway.
@en
Fluid flow induces mechanosens ...... h a PKCzeta-dependent pathway.
@nl
type
label
Fluid flow induces mechanosens ...... h a PKCzeta-dependent pathway.
@en
Fluid flow induces mechanosens ...... h a PKCzeta-dependent pathway.
@nl
prefLabel
Fluid flow induces mechanosens ...... h a PKCzeta-dependent pathway.
@en
Fluid flow induces mechanosens ...... h a PKCzeta-dependent pathway.
@nl
P2093
P2860
P1476
Fluid flow induces mechanosens ...... h a PKCzeta-dependent pathway.
@en
P2093
Amal K Dutta
Andrew P Feranchak
Charles Kresge
Kangmee Woo
Vishal Patel
P2860
P304
P356
10.1113/JPHYSIOL.2008.153015
P407
P577
2008-04-03T00:00:00Z