Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2.
about
Epigenetic principles and mechanisms underlying nervous system functions in health and diseaseClinical applications of epigenetics in cardiovascular disease: the long road aheadAnti-cancer activity of an osthole derivative, NBM-T-BMX-OS01: targeting vascular endothelial growth factor receptor signaling and angiogenesisHDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCsEffect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromastsTumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancerThe cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation.Hiding in plain view: the potential for commonly used drugs to reduce breast cancer mortality.Inhibiting HDAC1 Enhances the Anti-Cancer Effects of Statins through Downregulation of GGTase-Iβ ExpressionHDAC inhibition decreases the expression of EGFR in colorectal cancer cells.Computational Epigenetics: the new scientific paradigm.Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cellsInterplay between PKCδ and Sp1 on histone deacetylase inhibitor-mediated Epstein-Barr virus reactivation.Epigenetics and cardiovascular disease.PPemd26, an anthraquinone derivative, suppresses angiogenesis via inhibiting VEGFR2 signalling.Inhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21.Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifenInhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death.CD1d induction in solid tumor cells by histone deacetylase inhibitors through inhibition of HDAC1/2 and activation of Sp1idTarget: a web server for identifying protein targets of small chemical molecules with robust scoring functions and a divide-and-conquer docking approachBy recruiting HDAC1, MORC2 suppresses p21 Waf1/Cip1 in gastric cancer.Acetylation of HDAC1 and degradation of SIRT1 form a positive feedback loop to regulate p53 acetylation during heat-shock stress.A statin-regulated microRNA represses human c-Myc expression and function.Emerging molecular targets for brain repair after strokePI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanomaRosuvastatin Modulates the Post-Translational Acetylome in Endothelial CellsStatins Reduce the Risks of Relapse to Addiction in RatsLovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascadePrognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer.Dual Targeting of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Histone Deacetylase as a Therapy for Colorectal CancerSimvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond.Epigenetics primer: why the clinician should care about epigenetics.Autophagy, a novel target for chemotherapeutic intervention of thyroid cancer.Review structure- and dynamics-based computational design of anticancer drugs.Translational Perspective on Epigenetics in Cardiovascular Disease.HMG-CoA Reductase inhibitors: an updated review of patents of novel compounds and formulations (2011-2015).Sodium valproate induces cell senescence in human hepatocarcinoma cells.Cellular analysis of the action of epigenetic drugs and probes.Inactivation of HDAC3 and STAT3 is critically involved in 1-stearoyl-sn-glycero-3-phosphocholine-induced apoptosis in chronic myelogenous leukemia K562 cells.
P2860
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P2860
Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Statins increase p21 through i ...... f promoter-associated HDAC1/2.
@en
Statins increase p21 through i ...... f promoter-associated HDAC1/2.
@nl
type
label
Statins increase p21 through i ...... f promoter-associated HDAC1/2.
@en
Statins increase p21 through i ...... f promoter-associated HDAC1/2.
@nl
prefLabel
Statins increase p21 through i ...... f promoter-associated HDAC1/2.
@en
Statins increase p21 through i ...... f promoter-associated HDAC1/2.
@nl
P2093
P1433
P1476
Statins increase p21 through i ...... of promoter-associated HDAC1/2
@en
P2093
Chia-Wei Chou
Jung-Hsin Lin
Shu-Hao Yeh
Yi-Chu Lin
Yu-Fan Chang
P304
P356
10.1158/0008-5472.CAN-07-5807
P407
P577
2008-04-01T00:00:00Z