about
Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa DrugsThe design of rational combination chemotherapy for cancer.Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivationDisintegration of nascent replication bubbles during thymine starvation triggers RecA- and RecBCD-dependent replication origin destruction.Inhibition of the mammalian transcription factor LSF induces S-phase-dependent apoptosis by downregulating thymidylate synthase expression.Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.Future potential of thymidylate synthase inhibitors in cancer therapy.New approach to antifolate treatment of certain cancers as demonstrated in tissue culture.Influence of duration of exposure to 5-fluorouracil on antiproliferating activity against cultured murine lymphoma cellsMutagenic studies of folic acid antagonists.Multisubstrate adduct inhibitors: drug design and biological tools.Multiple mutant of Escherichia coli synthesizing virtually thymineless DNA during limited growth.Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331dUTPase inhibition augments replication defects of 5-Fluorouracil.Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism
P2860
Q28552781-F78B4819-9BEA-4ED4-A0C5-8AEF7C641FBAQ33581225-356E267A-308F-435D-8A7C-DB7B0F6FC6DFQ33726850-7C3ECB00-4110-4C54-B06A-7C52EBFEF868Q34276833-96B35EE4-091C-45D8-927F-B91849D451A7Q34488091-AA4FF84D-BF43-4145-8DE4-76C05CC37237Q34782000-06C4682C-137A-4243-A0C3-79E21DA6E8EBQ35011904-244230F0-CF41-4BC8-A4F1-9B055C17CD77Q35091573-C1BAC8D0-4920-4C86-8122-03CA206FCBBEQ36045743-F372F63D-CC76-4277-8F4F-7B687CE9E8BDQ36464801-FBF13A0C-0111-4FAD-A248-39F5CCD2690BQ37632419-74A73687-0BCB-42E5-92A2-AD4F7D14A2ECQ39935216-87B925B1-D6A6-4774-890D-B2BA2DBF5D30Q40859860-12E4C67E-F7EA-4D46-888F-8ED5E58BDBC0Q41767730-5B8B7DA4-D797-4458-8994-DFC054E09C76Q57175017-275C3925-2BD1-445A-8BA8-6D467CBAD71E
P2860
description
1971 nî lūn-bûn
@nan
1971年の論文
@ja
1971年学术文章
@wuu
1971年学术文章
@zh-cn
1971年学术文章
@zh-hans
1971年学术文章
@zh-my
1971年学术文章
@zh-sg
1971年學術文章
@yue
1971年學術文章
@zh
1971年學術文章
@zh-hant
name
On the nature of thymineless death.
@en
type
label
On the nature of thymineless death.
@en
prefLabel
On the nature of thymineless death.
@en
P2860
P1476
On the nature of thymineless death.
@en
P2093
P2860
P304
P356
10.1111/J.1749-6632.1971.TB31155.X
P407
P577
1971-11-01T00:00:00Z