about
Functional consequences of a carboxyl terminal missense mutation Arg278Cys in human cardiac troponin TCardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitizationDifferentiation-inducing factor-1 induces cyclin D1 degradation through the phosphorylation of Thr286 in squamous cell carcinomaFamilial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivityA novel mechanism of JNK1 activation. Nuclear translocation and activation of JNK1 during ischemia and reperfusionCa(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.Survival benefit of ghrelin in the heart failure due to dilated cardiomyopathy.Biological actions of green tea catechins on cardiac troponin C.Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression.Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model.Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model miceStage-dependent benefits and risks of pimobendan in mice with genetic dilated cardiomyopathy and progressive heart failure.Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathyMolecular pathogenic mechanisms of cardiomyopathies caused by mutations in cardiac troponin T.Sarcomeric proteins and inherited cardiomyopathies.Troponin: regulatory function and disorders.Inherited cardiomyopathies caused by troponin mutations.Wnt/β-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box O.DIF-1 inhibits tumor growth in vivo reducing phosphorylation of GSK-3β and expressions of cyclin D1 and TCF7L2 in cancer model mice.Differentiation-inducing factor-1 suppresses the expression of c-Myc in the human cancer cell lines.DIF-1 inhibits the Wnt/β-catenin signaling pathway by inhibiting TCF7L2 expression in colon cancer cell lines.Anti-angiogenic effects of differentiation-inducing factor-1 involving VEGFR-2 expression inhibition independent of the Wnt/β-catenin signaling pathway.Celecoxib-induced degradation of T-cell factors-1 and -4 in human colon cancer cells.Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins.Targeted Genome Replacement via Homology-directed Repair in Non-dividing Cardiomyocytes.Celecoxib induces apoptosis by inhibiting the expression of survivin in HeLa cells.Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines.Differentiation-inducing factor-1 suppresses gene expression of cyclin D1 in tumor cells.Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3beta and degrades cyclin D1 in mammalian cells.Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo.Cardiomyopathies: classification, clinical characterization, and functional phenotypes.Endogenous cardiac troponin T modulates Ca(2+)-mediated smooth muscle contraction.Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy.Dictyostelium differentiation-inducing factor-1 binds to mitochondrial malate dehydrogenase and inhibits its activity.A pH-sensitive interaction of troponin I with troponin C coupled with strongly binding cross-bridges in cardiac myofilament activation.Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ΔK210.Staurosporine-induced cleavage of alpha-smooth muscle actin during myofibroblast apoptosis.Troponin I inhibitory peptide suppresses the force generation in smooth muscle by directly interfering with cross-bridge formation.Glycogen synthase kinase-3beta is tyrosine-phosphorylated by MEK1 in human skin fibroblasts.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Sachio Morimoto
@ast
Sachio Morimoto
@en
Sachio Morimoto
@es
Sachio Morimoto
@sl
type
label
Sachio Morimoto
@ast
Sachio Morimoto
@en
Sachio Morimoto
@es
Sachio Morimoto
@sl
prefLabel
Sachio Morimoto
@ast
Sachio Morimoto
@en
Sachio Morimoto
@es
Sachio Morimoto
@sl
P106
P21
P31
P496
0000-0001-9171-3636
P569
2000-01-01T00:00:00Z