NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42. - Wikidata - awgldk - TriplyDB

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

http://www.wikidata.org/entity/Q40014779

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Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption.MicroRNA: Implications for Alzheimer Disease and other Human CNS Disorders Signaling effect of amyloid-beta(42) on the processing of AbetaPP Neuroinflammation in Alzheimer's disease Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD Novel Nuclear Factor-KappaB Targeting Peptide Suppresses β-Amyloid Induced Inflammatory and Apoptotic Responses in Neuronal Cells The normal and pathologic roles of the Alzheimer's β-secretase, BACE1 Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in mice Differential spatio-temporal regulation of MMPs in the 5xFAD mouse model of Alzheimer's disease: evidence for a pro-amyloidogenic role of MT1-MMP.Two novel DNA motifs are essential for BACE1 gene transcription The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation.Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits.Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells.Edaravone alleviates Alzheimer's disease-type pathologies and cognitive deficits Bee venom ameliorates lipopolysaccharide-induced memory loss by preventing NF-kappaB pathway.All-trans-retinoic acid reduces BACE1 expression under inflammatory conditions via modulation of nuclear factor κB (NFκB) signaling.Concurrent Treatment with Taxifolin and Cilostazol on the Lowering of β-Amyloid Accumulation and Neurotoxicity via the Suppression of P-JAK2/P-STAT3/NF-κB/BACE1 Signaling Pathways.Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's disease Advances in the pathogenesis of Alzheimer's disease: a re-evaluation of amyloid cascade hypothesis.Leptin signaling and Alzheimer's disease.p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer's disease Mutant presenilin 1 increases the expression and activity of BACE1 Trientine reduces BACE1 activity and mitigates amyloidosis via the AGE/RAGE/NF-κB pathway in a transgenic mouse model of Alzheimer's disease.MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro Can BACE1 inhibition mitigate early axonal pathology in neurological diseases?Is BACE1 a suitable therapeutic target for the treatment of Alzheimer's disease? Current strategies and future directions.Regulation of β cleavage of amyloid precursor protein Amyloid-β production: major link between oxidative stress and BACE1.Review: unchained maladie - a reassessment of the role of Ubb(+1) -capped polyubiquitin chains in Alzheimer's disease.Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer's disease.Epigenetic treatment of neurological disease.NF-κB signaling pathways: role in nervous system physiology and pathology.From mitochondrial dysfunction to amyloid beta formation: novel insights into the pathogenesis of Alzheimer's disease.Transcriptional and post-transcriptional regulation of β-secretase.Oxidative Stress in Alzheimer's Disease: Should We Keep Trying Antioxidant Therapies?Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis.Pomegranate inhibits neuroinflammation and amyloidogenesis in IL-1β-stimulated SK-N-SH cells.

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P2860

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

http://www.wikidata.org/entity/Q40014779

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

@en

type

label

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

@en

prefLabel

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

@en

P1433

Q40014779-55B9BB6D-7C88-4ECF-9758-93DE2A6402B6

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P2860

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P356

P1433

Journal of Biological Chemistry

P1476

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

@en

P2093

Jean Sevalle

http://www.w3.org/2001/XMLSchema#string

Steffen Rossner

http://www.w3.org/2001/XMLSchema#string

Virginie Buggia-Prevot

http://www.w3.org/2001/XMLSchema#string

P2860

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

Purification and cloning of amyloid precursor protein beta-secretase from human brain

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

P304

10037-10047

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P31

scholarly article

P356

10.1074/JBC.M706579200

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P407

P433

15

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P478

283

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Frédéric Checler

P577

2008-02-08T00:00:00Z

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P698

18263584

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