The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation.
about
NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptorsA new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding proteinPSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptorsPurification and characterization of the human interleukin-18 receptorDomain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation.Nuclear receptor corepressorsCharacterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factorInteractions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivatorIn silico discovery of novel retinoic acid receptor agonist structuresRequirement of helix 1 and the AF-2 domain of the thyroid hormone receptor for coactivation by PGC-1New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acidThyroid hormone response element sequence and the recruitment of retinoid X receptors for thyroid hormone responsiveness.Therapeutic Implications of PPARgamma in Human Osteosarcoma.Regulation of the mdm2 oncogene by thyroid hormone receptorRational discovery of novel nuclear hormone receptor antagonists.A 10-amino-acid sequence in the N-terminal A/B domain of thyroid hormone receptor alpha is essential for transcriptional activation and interaction with the general transcription factor TFIIB.A shift in the ligand responsiveness of thyroid hormone receptor alpha induced by heterodimerization with retinoid X receptor alphaActivation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states.Mutations in the conserved C-terminal sequence in thyroid hormone receptor dissociate hormone-dependent activation from interference with AP-1 activity.Constitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression.Pathways of retinoid synthesis in mouse macrophages and bone marrow cellsNegative response elements in keratin genes mediate transcriptional repression and the cross-talk among nuclear receptors.Activation of the prolactin gene by peroxisome proliferator-activated receptor-alpha appears to be DNA binding-independent.Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression.PPARγ signaling and emerging opportunities for improved therapeutics.A novel role for helix 12 of retinoid X receptor in regulating repression.Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer.Novel receptor interaction and repression domains in the orphan receptor SHP.Novel roles of retinoid X receptor (RXR) and RXR ligand in dynamically modulating the activity of the thyroid hormone receptor/RXR heterodimer.SNP mutations occurring in thyroid hormone receptor influenced individual susceptibility to triiodothyronine: Molecular dynamics and site-directed mutagenesis approaches.PPAR delta agonists stimulate oligodendrocyte differentiation in tissue culture.Regulation of Oligodendrocyte Differentiation and Myelination by Nuclear Receptors: Role in Neurodegenerative Disorders.PPAR Tissue Distribution and Interactions with Other Hormone-Signaling Pathways
P2860
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P2860
The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
The ligand-binding domains of ...... ilencing, and transactivation.
@en
type
label
The ligand-binding domains of ...... ilencing, and transactivation.
@en
prefLabel
The ligand-binding domains of ...... ilencing, and transactivation.
@en
P2093
P2860
P356
P1476
The ligand-binding domains of ...... ilencing, and transactivation.
@en
P2093
H H Samuels
M E Greene
V Desai-Yajnik
P2860
P304
P356
10.1128/MCB.15.3.1817
P407
P577
1995-03-01T00:00:00Z