Inhibition of Bcr serine kinase by tyrosine phosphorylation.
about
Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo.Co-expression with BCR induces activation of the FES tyrosine kinase and phosphorylation of specific N-terminal BCR tyrosine residuesThe Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domainBcr-Abl with an SH3 deletion retains the ability To induce a myeloproliferative disease in mice, yet c-Abl activated by an SH3 deletion induces only lymphoid malignancyExpression of bcr-abl mRNA in individual chronic myelogenous leukaemia cells as determined by in situ amplification.CD148, a new membrane tyrosine phosphatase involved in leukocyte function.The NH(2)-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-AblPreparation and application of antibodies to phosphoamino acid sequences.Bcr is a negative regulator of the Wnt signalling pathwayJanus kinase 2 regulates Bcr-Abl signaling in chronic myeloid leukemia.Bcr: a negative regulator of the Bcr-Abl oncoprotein in leukemia.Studying the pathogenesis of BCR-ABL+ leukemia in mice.The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemiaBCR: a new target in resistance mediated by BCR/ABL-315I?Opening the door to the development of novel Abl kinase inhibitors.Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning.Kinase domain mutants of Bcr enhance Bcr-Abl oncogenic effects.Polarized distribution of Bcr-Abl in migrating myeloid cells and co-localization of Bcr-Abl and its target proteins.BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model.Antagonistic effects of ABL and BCRABL proteins on proliferation and the response to genotoxic stress in normal and leukemic myeloid cells.Molecular processes involved in B cell acute lymphoblastic leukaemia.
P2860
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P2860
Inhibition of Bcr serine kinase by tyrosine phosphorylation.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Inhibition of Bcr serine kinase by tyrosine phosphorylation.
@en
type
label
Inhibition of Bcr serine kinase by tyrosine phosphorylation.
@en
prefLabel
Inhibition of Bcr serine kinase by tyrosine phosphorylation.
@en
P2093
P2860
P356
P1476
Inhibition of Bcr serine kinase by tyrosine phosphorylation.
@en
P2093
N Heisterkamp
R B Arlinghaus
P2860
P304
P356
10.1128/MCB.16.3.998
P407
P577
1996-03-01T00:00:00Z