The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases.
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Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylationElucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinasesThe mTOR signalling pathway in human cancerDual requirement for a newly identified phosphorylation site in p70s6kProtein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated proteinRAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsSalicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigenRegulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation siteStructure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif siteCurrent development of mTOR inhibitors as anticancer agentsCurcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cellsRapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25Metabolic regulation of manganese superoxide dismutase expression via essential amino acid deprivationFRAP/mTOR is required for proliferation and patterning during embryonic development in the mouseU12, a UDCA derivative, acts as an anti-hepatoma drug lead and inhibits the mTOR/S6K1 and cyclin/CDK complex pathwaysExpression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophyRapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardiumAmino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanismTOR signaling.Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway.Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner.PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle.The nuclear receptor DHR3 modulates dS6 kinase-dependent growth in DrosophilaDynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation.Divergent Anabolic Signalling responses of Murine Soleus and Tibialis Anterior Muscles to Chronic 2G Hypergravity.Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo.4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle.The cancerous translation apparatusThe target of rapamycin (TOR) proteinsThe modular phosphorylation and activation of p70s6k.Analysis of 65 tuberous sclerosis complex (TSC) patients by TSC2 DGGE, TSC1/TSC2 MLPA, and TSC1 long-range PCR sequencing, and report of 28 novel mutations.Curcumin disrupts the Mammalian target of rapamycin-raptor complex.Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.Elevated corticosterone associated with food deprivation upregulates expression in rat skeletal muscle of the mTORC1 repressor, REDD1.Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome.
P2860
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P2860
The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The principal rapamycin-sensit ...... in-insensitive kinase kinases.
@en
type
label
The principal rapamycin-sensit ...... in-insensitive kinase kinases.
@en
prefLabel
The principal rapamycin-sensit ...... in-insensitive kinase kinases.
@en
P2093
P2860
P356
P1476
The principal rapamycin-sensit ...... in-insensitive kinase kinases.
@en
P2093
P2860
P304
P356
10.1128/MCB.16.11.6242
P407
P577
1996-11-01T00:00:00Z