Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy
about
MEF2C silencing attenuates load-induced left ventricular hypertrophy by modulating mTOR/S6K pathway in miceLKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis.Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function.Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathwaysThe lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling.Reactive nitrogen species is required for the activation of the AMP-activated protein kinase by statin in vivoInsulin signalling in the heart.LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunctionEndothelial cell-specific liver kinase B1 deletion causes endothelial dysfunction and hypertension in mice in vivo.LKB1 loss of function studied in vivo.Resveratrol in cardiovascular disease: what is known from current research?The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signalingTargeting the energy guardian AMPK: another avenue for treating cardiomyopathy?Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt.Differential AMPK phosphorylation sites associated with phenylephrine vs. antihypertrophic effects of adenosine agonists in neonatal rat ventricular myocytes.Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle.SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis.Increased CD36 expression in middle-aged mice contributes to obesity-related cardiac hypertrophy in the absence of cardiac dysfunction.
P2860
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P2860
Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy
description
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im März 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/03/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/03/01)
@nl
наукова стаття, опублікована в березні 2007
@uk
مقالة علمية (نشرت في مارس 2007)
@ar
name
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@ast
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@en
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@nl
type
label
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@ast
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@en
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@nl
prefLabel
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@ast
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@en
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@nl
P2093
P2860
P1476
Expression of an active LKB1 c ...... nylephrine-induced hypertrophy
@en
P2093
Amy J. Barr
Anna A. Noga
Carrie-Lynn M. Soltys
Gary D. Lopaschuk
Jason R. B. Dyck
Suzanne Kovacic
P2860
P304
H1460–1469
P356
10.1152/AJPHEART.01133.2006
P577
2007-03-01T00:00:00Z