The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies.
about
Potential roles for prions and protein-only inheritance in cancerLigand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins.Characterization of the response of primary cells relevant to dialysis-related amyloidosis to β2-microglobulin monomer and fibrils.Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivationPositive cooperative mechanistic binding of proteins at low concentrations: a comparison of poly (sodium N-undecanoyl sulfate) and sodium dodecyl sulfate.Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.Mild exposure of RIN-5F β-cells to human islet amyloid polypeptide aggregates upregulates antioxidant enzymes via NADPH oxidase-RAGE: an hormetic stimulus.Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressorThe aggregation of mutant p53 produces prion-like properties in cancer.A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems.The "Jekyll and Hyde" Actions of Nucleic Acids on the Prion-like Aggregation of Proteins.Role of p53 isoforms and aggregations in cancer.Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?Interaction of an anticancer peptide fragment of azurin with p53 and its isolated domains studied by atomic force spectroscopy.Embryonic stem and haematopoietic progenitor cells resist to Aβ oligomer toxicity and maintain the differentiation potency in culture.p53 Aggregates penetrate cells and induce the co-aggregation of intracellular p53.Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant.p53 Isoforms and Their Implications in Cancer
P2860
Q26825056-24493F8E-DF01-4036-8488-6D1834546AABQ33671560-0FBC3A2E-775F-4704-8179-64E2F77FE6E3Q34077850-C0BF63B0-A665-462E-8AB7-2DE39893F0BDQ34452519-C25B189A-B6B1-401D-990C-631C1BBAE259Q35211288-3517B67C-D34A-4270-87D9-7A117E7C2610Q36201740-6701EF74-6CC2-4737-A917-2CDEC9627BF9Q37459532-1AFC6C86-C88A-43C6-AB41-12CD22489797Q38134099-E4697AC8-224D-4418-B698-5B63F353E040Q38186535-7D13D2AF-4040-49A4-8E6A-DCB9D365D2A4Q38752375-EC68B789-903B-4D4F-83F3-FBC2F4C1B9E4Q38861978-1305E284-D5A2-469C-8CF6-C490B8DD3A48Q38883419-B577CB0C-1F4A-4718-9883-67CC86B011FEQ38934098-D8994EC3-9829-4FCC-912C-EEECCC4F1C31Q39598993-24C129C7-0AAA-4259-9C72-2AF1235F00BEQ39633631-CC79D789-FD8F-424D-8682-3E1C5B902C3BQ42255562-9EC4DF30-BFB3-4B24-BC70-77ECE962F564Q46588576-78DD28F0-82E5-4CCF-8B7C-DE813BF6E54FQ58702684-482F5BE0-3B9B-42FF-9B9E-CB06A88F9734
P2860
The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The (1-63) region of the p53 t ...... cytotoxic amyloid assemblies.
@en
type
label
The (1-63) region of the p53 t ...... cytotoxic amyloid assemblies.
@en
prefLabel
The (1-63) region of the p53 t ...... cytotoxic amyloid assemblies.
@en
P2093
P2860
P1433
P1476
The (1-63) region of the p53 t ...... o cytotoxic amyloid assemblies
@en
P2093
Alessandra Gliozzi
Alessandra Pesce
Andrea Berti
Annalisa Relini
Stefania Rigacci
P2860
P304
P356
10.1529/BIOPHYSJ.107.122283
P407
P577
2008-01-16T00:00:00Z