Intracellular cholesterol modifies the ERAD of glucocerebrosidase in Gaucher disease patients.
about
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyA mutation in SCARB2 is a modifier in Gaucher diseaseThe pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of beta-glucosidase.Exploring the link between glucocerebrosidase mutations and parkinsonismAcidic Ca2+ stores in neurodegeneration.Histone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperonesVAMP-associated Proteins (VAP) as Receptors That Couple Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Proteostasis with Lipid Homeostasis.Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson diseaseChemical and/or biological therapeutic strategies to ameliorate protein misfolding diseasesGaucher disease paradigm: from ERAD to comorbidity.Parkinson's disease: acid-glucocerebrosidase activity and alpha-synuclein clearance.Unfolded protein response in Gaucher disease: from human to Drosophila.The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson's Disease.Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB.Ambroxol as a pharmacological chaperone for mutant glucocerebrosidase.Cytoplasmic nanojunctions between lysosomes and sarcoplasmic reticulum are required for specific calcium signalingN370S-GBA1 mutation causes lysosomal cholesterol accumulation in Parkinson's disease.Tissue Specificity: The Role of Organellar Membrane Nanojunctions in Smooth Muscle Ca2+ Signaling.Protein Trafficking DiseasesIs Parkinson's disease a lysosomal disorder?
P2860
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P2860
Intracellular cholesterol modifies the ERAD of glucocerebrosidase in Gaucher disease patients.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Intracellular cholesterol modi ...... e in Gaucher disease patients.
@en
type
label
Intracellular cholesterol modi ...... e in Gaucher disease patients.
@en
prefLabel
Intracellular cholesterol modi ...... e in Gaucher disease patients.
@en
P1476
Intracellular cholesterol modi ...... e in Gaucher disease patients.
@en
P2093
Mia Horowitz
P304
P356
10.1016/J.YMGME.2007.10.132
P577
2007-12-21T00:00:00Z