Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach.
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Role of Nrf2 in oxidative stress and toxicityNrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagyNrf2 expression is increased in peripheral blood mononuclear cells derived from mild-moderate ex-smoker COPD patients with persistent oxidative stressKnockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis.Cigarette smoke alters the secretome of lung epithelial cells.Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cellsComparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.From proteomics to prescription-the search for COPD biomarkers.Protein thiol oxidation in murine airway epithelial cells in response to naphthalene or diethyl maleateHeightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity.Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers.Application of proteomics and peptidomics to COPD.The ER stress transducer IRE1β is required for airway epithelial mucin productionProteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients.Formation of covalently bound protein adducts from the cytotoxicant naphthalene in nasal epithelium: species comparisonsA computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue.Autoreactivity to glucose regulated protein 78 links emphysema and osteoporosis in smokersAcrolein induces endoplasmic reticulum stress and causes airspace enlargement.A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.Proteomic analysis of whole human saliva detects enhanced expression of interleukin-1 receptor antagonist, thioredoxin and lipocalin-1 in cigarette smokers compared to non-smokers.Identification of oxidative stress related proteins as biomarkers for lung cancer and chronic obstructive pulmonary disease in bronchoalveolar lavage.PKR-dependent CHOP induction limits hyperoxia-induced lung injury.Resveratrol exerts an anti-apoptotic effect on human bronchial epithelial cells undergoing cigarette smoke exposure.Effects in cigarette smoke stimulated bronchial epithelial cells of a corticosteroid entrapped into nanostructured lipid carriers.Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2.Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated processCritical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysemaComparative proteome analysis of peripheral neutrophils from sulfur mustard-exposed and COPD patients.Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta.APC +/- alters colonic fibroblast proteome in FAP.Smoking and idiopathic pulmonary fibrosisAnalysis of the plasma proteome in COPD: Novel low abundance proteins reflect the severity of lung remodeling.Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease.Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation.Oxidative stress response and Nrf2 signaling in aging.Disruption of NAD(+) binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactionsAdverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide IsomeraseCalreticulin translocation aggravates endoplasmic reticulum stress-associated apoptosis during cardiomyocyte hypoxia/reoxygenation.Calreticulin regulates transforming growth factor-β-stimulated extracellular matrix production.The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome.
P2860
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P2860
Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cigarette smoke induces an unf ...... an lung: a proteomic approach.
@en
type
label
Cigarette smoke induces an unf ...... an lung: a proteomic approach.
@en
prefLabel
Cigarette smoke induces an unf ...... an lung: a proteomic approach.
@en
P2093
P2860
P356
P1476
Cigarette smoke induces an unf ...... an lung: a proteomic approach.
@en
P2093
Chunli Liu
Oscar Perez
Salim Merali
Steven G Kelsen
Xunbao Duan
P2860
P304
P356
10.1165/RCMB.2007-0221OC
P577
2007-12-13T00:00:00Z