Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands.
about
EOGT and O-GlcNAc on secreted and membrane proteins.Biological functions of fucose in mammals.The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking.Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis.Inhibition of Delta-induced Notch signaling using fucose analogs.The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.Notch Signaling in Development, Tissue Homeostasis, and Disease.Notch signaling: A sweet strategy.Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features.Signal Transduction: Notch catches a Jagged edge.Congenital diseases caused by defective -glycosylation of Notch receptors
P2860
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P248
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P2860
Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Deciphering the Fringe-Mediate ...... iscrimination between Ligands.
@en
type
label
Deciphering the Fringe-Mediate ...... iscrimination between Ligands.
@en
prefLabel
Deciphering the Fringe-Mediate ...... iscrimination between Ligands.
@en
P2860
P921
P1433
P1476
Deciphering the Fringe-Mediate ...... iscrimination between Ligands.
@en
P2093
Robert S Haltiwanger
Shinako Kakuda
P2860
P304
P356
10.1016/J.DEVCEL.2016.12.013
P407
P577
2016-12-29T00:00:00Z