Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
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Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during InflammationIs the risk of cardiovascular disease altered with anti-inflammatory therapies? Insights from rheumatoid arthritisScanning for Therapeutic Targets within the Cytokine Network of Idiopathic Inflammatory MyopathiesPreclinical validation of interleukin 6 as a therapeutic target in multiple myelomaSpotlight on tocilizumab and its potential in the treatment of systemic sclerosisInflammation induced loss of skeletal muscleContribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis.N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An UpdateIL-6 and MYC collaborate in plasma cell tumor formation in mice.IL-6 and high glucose synergistically upregulate MMP-1 expression by U937 mononuclear phagocytes via ERK1/2 and JNK pathways and c-Jun.Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice.n-3 PUFAs reduce T-helper 17 cell differentiation by decreasing responsiveness to interleukin-6 in isolated mouse splenic CD4⁺ T cells.IL-6 in diabetes and cardiovascular complications.The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation.Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training.Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitisInterleukin-1β and interleukin-6 in arthritis animal models: roles in the early phase of transition from acute to chronic inflammation and relevance for human rheumatoid arthritisgp130 at the nexus of inflammation, autoimmunity, and cancer.Impact of interleukin-6 in hematological malignancies.Increased CD40+ Fibrocytes in Patients With Idiopathic Orbital Inflammation.Intestinal alkaline phosphatase has beneficial effects in mouse models of chronic colitisViral interleukin-6: role in Kaposi's sarcoma-associated herpesvirus: associated malignancies.The Sbi Protein Contributes to Staphylococcus aureus Inflammatory Response during Systemic Infection.Chronic inflammation in cancer development.Cutting edge: IL-6 is a marker of inflammation with no direct role in inflammasome-mediated mouse modelsVagal nerve stimulation blocks interleukin 6-dependent synaptic hyperexcitability induced by lipopolysaccharide-induced acute stress in the rodent prefrontal cortex.IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality.Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.Identification of STOML2 as a putative novel asthma risk gene associated with IL6R.Roles of IL-6-gp130 Signaling in Vascular Inflammation.Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cellsInhibition of IL-6 family cytokines by SOCS3.Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.Increased inflammation and impaired resistance to Chlamydophila pneumoniae infection in Dusp1(-/-) mice: critical role of IL-6.IL-6/IL-6 receptor system and its role in physiological and pathological conditions.Hitting a complex target: an update on interleukin-6 trans-signalling.IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.Targeting gp130 to prevent inflammation and promote insulin action.The effect of inflammatory cytokines in alcoholic liver disease.
P2860
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P2860
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
@en
type
label
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
@en
prefLabel
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
@en
P2093
P1433
P1476
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
@en
P2093
Anwen S Williams
Athena Chalaris
Björn Rabe
Dirk Seegert
Georg H Waetzig
Jürgen Scheller
Ulrike May
P304
P356
10.1182/BLOOD-2007-07-102137
P407
P577
2007-11-07T00:00:00Z