Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.
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Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90IL-8-induced neutrophil chemotaxis is mediated by Janus kinase 3 (JAK3)Flavones: From Biosynthesis to Health BenefitsThe Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of MesotheliumNon-Nutrient, Naturally Occurring Phenolic Compounds with Antioxidant Activity for the Prevention and Treatment of Periodontal DiseasesCurcumin and Apigenin - novel and promising therapeutics against chronic neuroinflammation in Alzheimer's diseasePlant-derived immunomodulators: an insight on their preclinical evaluation and clinical trialsCancer prevention with promising natural products: mechanisms of action and molecular targetsTranscriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and DiversityOptimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolitesJNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheetInhibition of nitric oxide production in LPS-stimulated RAW 264.7 cells by stem bark of Ulmus pumila L.Genkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages.Flavone deglycosylation increases their anti-inflammatory activity and absorption.Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonismStudies on the health impact of Agrimonia procera in piglets.Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor κB-activated tumor necrosis factor-α production via regulation of p65 serine 536 phosphorylation.Advances in treatment of ulcerative colitis with herbs: from bench to bedsideAntioxidant, inhibition of α-glucosidase and suppression of nitric oxide production in LPS-induced murine macrophages by different fractions of Actinidia arguta stem.Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets.Anti-inflammatory effect of the water fraction from hawthorn fruit on LPS-stimulated RAW 264.7 cellsFlavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages.Nutraceutical Supplements for Inflammatory Bowel Disease.miR-628, a microRNA that is induced by Toll-like receptor stimulation, regulates porcine innate immune responsesChemoprevention in gastrointestinal physiology and disease. Targeting the progression of cancer with natural products: a focus on gastrointestinal cancer.NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.Extracts of six Rubiaceae species combined with rifampicin have good in vitro synergistic antimycobacterial activity and good anti-inflammatory and antioxidant activitiesVaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NFκB and ERK pathways in Raw 264.7 cells.Allium hookeri root extract exerts anti-inflammatory effects by nuclear factor-κB down-regulation in lipopolysaccharide-induced RAW264.7 cells.Resveratrol as a Bioenhancer to Improve Anti-Inflammatory Activities of Apigenin.TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation.Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function.Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions.Apigenin Ameliorates Dyslipidemia, Hepatic Steatosis and Insulin Resistance by Modulating Metabolic and Transcriptional Profiles in the Liver of High-Fat Diet-Induced Obese Mice.Activation of PPARγ by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage PolarizationApigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cellsApigenin protects endothelial cells from lipopolysaccharide (LPS)-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial functionApigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner.Recent developments in anti-inflammatory natural products.Targeting innate immunity protein kinase signalling in inflammation.
P2860
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P2860
Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Apigenin blocks lipopolysaccha ...... ession of p65 phosphorylation.
@en
type
label
Apigenin blocks lipopolysaccha ...... ession of p65 phosphorylation.
@en
prefLabel
Apigenin blocks lipopolysaccha ...... ession of p65 phosphorylation.
@en
P2093
P1476
Apigenin blocks lipopolysaccha ...... ression of p65 phosphorylation
@en
P2093
Andrea I Doseff
Denis C Guttridge
Erich Grotewold
Mark D Wewers
Melissa A Vargo
Mikhail A Gavrilin
Oliver H Voss
Sanjay Batra
P304
P356
10.4049/JIMMUNOL.179.10.7121
P407
P577
2007-11-01T00:00:00Z