Targeting innate immunity protein kinase signalling in inflammation. - Wikidata - awgldk - TriplyDB

Targeting innate immunity protein kinase signalling in inflammation.

Targeting innate immunity protein kinase signalling in inflammation.

http://www.wikidata.org/entity/Q37502685

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p38γ and p38δ Mitogen Activated Protein Kinases (MAPKs), New Stars in the MAPK Galaxy The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis Crystal structure of the p38α MAP kinase in complex with a docking peptide from TAB1 Mechanisms of drug resistance in kinases.Pim kinase inhibitors: a survey of the patent literature LASSBio-1135: a dual TRPV1 antagonist and anti-TNF-alpha compound orally effective in models of inflammatory and neuropathic pain Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK The diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitor Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation Microchannel acoustophoresis does not impact survival or function of microglia, leukocytes or tumor cells.Does activation of the FcgammaRIIa play a role in the pathogenesis of the acute lung injury/acute respiratory distress syndrome?Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats The MAP kinase-activated protein kinase 2 (MK2) contributes to the Shiga toxin-induced inflammatory response Anti-inflammatory effects of ursodeoxycholic acid by lipopolysaccharide-stimulated inflammatory responses in RAW 264.7 macrophages.TNF and MAP kinase signalling pathways.Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1.Differential induction of innate immune responses by synthetic lipid a derivatives Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon.N-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression.IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation.Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.Protective effect of the methanol extract from Cryptotaenia japonica Hassk. against lipopolysaccharide-induced inflammation in vitro and in vivo Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models Analytical challenges translating mass spectrometry-based phosphoproteomics from discovery to clinical applications.Measles contributes to rheumatoid arthritis: evidence from pathway and network analyses of genome-wide association studies.Role of RNA-Binding Proteins in MAPK Signal Transduction Pathway.Pharmacological inhibition of TPL2/MAP3K8 blocks human cytotoxic T lymphocyte effector functions.c-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies The role of endosomal escape and mitogen-activated protein kinases in adenoviral activation of the innate immune response.Tissue-Specific Regulation of p38α-Mediated Inflammation in Con A-Induced Acute Liver Damage.Extracellular milieu grossly alters pathogen-specific immune response of mammary epithelial cells.Computational Prediction and Validation of BAHD1 as a Novel Molecule for Ulcerative Colitis.The p38 MAP Kinase Family as Regulators of Proinflammatory Cytokine Production in Degenerative Diseases of the CNS.Biodistribution and Efficacy of Targeted Pulmonary Delivery of a Protein Kinase C-δ Inhibitory Peptide: Impact on Indirect Lung Injury.p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor-activated macrophages The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS.The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.Enzymatically-Processed Wheat Bran Enhances Macrophage Activity and Has in Vivo Anti-Inflammatory Effects in Mice.

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Targeting innate immunity protein kinase signalling in inflammation.

http://www.wikidata.org/entity/Q37502685

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on June 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Targeting innate immunity protein kinase signalling in inflammation.

@en

Targeting innate immunity protein kinase signalling in inflammation.

@nl

type

label

Targeting innate immunity protein kinase signalling in inflammation.

@en

Targeting innate immunity protein kinase signalling in inflammation.

@nl

prefLabel

Targeting innate immunity protein kinase signalling in inflammation.

@en

Targeting innate immunity protein kinase signalling in inflammation.

@nl

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Nature Reviews Drug Discovery

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Targeting innate immunity protein kinase signalling in inflammation.

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P2860

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation.

Dynamic protein associations define two phases of IL-1beta transcriptional activation.

Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.

Endotoxin tolerance disrupts chromatin remodeling and NF-kappaB transactivation at the IL-1beta promoter.

Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection.

Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation.

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480-499

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scholarly article

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10.1038/NRD2829

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6

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8

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Matthias Gaestel

Alexey Kotlyarov

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2009-06-01T00:00:00Z

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26254592

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19483709

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