Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina. - Wikidata - awgldk - TriplyDB

Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina.

Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina.

http://www.wikidata.org/entity/Q40071488

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Vsx2 in the zebrafish retina: restricted lineages through derepression.Enhanced generation of retinal progenitor cells from human retinal pigment epithelial cells induced by amniotic fluid.Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.Mouse retinal development: a dark horse model for systems biology research Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells.Cyclin D1 inactivation extends proliferation and alters histogenesis in the postnatal mouse retina MicroRNA-20a is essential for normal embryogenesis by targeting vsx1 mRNA in fish Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina.Coordinating progenitor cell cycle exit and differentiation in the developing vertebrate retina Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression.Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina.Reconciling competence and transcriptional hierarchies with stochasticity in retinal lineages.Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development.The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina.Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis.Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina.Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence.Lhx2 links the intrinsic and extrinsic factors that control optic cup formation.Regulation of WNT Signaling by VSX2 During Optic Vesicle Patterning in Human Induced Pluripotent Stem Cells.Sequence divergence in the 3'-untranslated region has an effect on the subfunctionalization of duplicate genes.Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis

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P2860

Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina.

http://www.wikidata.org/entity/Q40071488

description

2007 nî lūn-bûn

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2007年学术文章

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Negative regulation of Vsx1 by ...... erved in the vertebrate retina

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Anna M Clark

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Eric S Veien

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Richard I Dorsky

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Robert L Chow

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Sanghee Yun

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Yuan Y Wu

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P2860

Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF

rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina

Stages of embryonic development of the zebrafish

Human microphthalmia associated with mutations in the retinal homeobox gene CHX10

CHX10 mutations cause non-syndromic microphthalmia/ anophthalmia in Arab and Jewish kindreds

CHX10 targets a subset of photoreceptor genes

Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation

Transcriptional activity of the paired-like homeodomain proteins CHX10 and VSX1

Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity

Nuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion.

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