Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture.

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Curcumin mitigates axonal injury and neuronal cell apoptosis through the PERK/Nrf2 signaling pathway following diffuse axonal injury.Adapted HCV JFH1 variant is capable of accommodating a large foreign gene insert and allows lower level HCV replication and viral production

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Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture.

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Activation of PERK-Nrf2 oncoge ...... istently infected HCV culture.

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type

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Activation of PERK-Nrf2 oncoge ...... istently infected HCV culture.

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Activation of PERK-Nrf2 oncoge ...... istently infected HCV culture.

@en

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Activation of PERK-Nrf2 oncoge ...... istently infected HCV culture.

@en

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Curt H Hagedorn

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Donkita Danielle Williams

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Hua Lu

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Krzysztof Moroz

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Krzysztof Reiss

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Luis A Balart

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Milad Chedid

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Shuanghu Liu

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Srikanta Dash

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Srinivas Chava

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Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

Mdm2 promotes the rapid degradation of p53

Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

Activation of chaperone-mediated autophagy during oxidative stress

Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival

Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response

Molecular mechanisms underlying RB protein function

Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase

Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

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s41598-017-10087-6

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scholarly article

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10.1038/S41598-017-10087-6

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English

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Suchitra Sumitran-Holgersson

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2017-08-23T00:00:00Z

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28835697

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5569052

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Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture.

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P2860

P2860

Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture.

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

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P577

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

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P577

P698

P932