The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication. - Wikidata - awgldk - TriplyDB

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

http://www.wikidata.org/entity/Q40075782

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Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication Adeno-associated Virus as a Mammalian DNA Vector Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins The effect of DNA-dependent protein kinase on adeno-associated virus replication Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction.Systemic delivery of shRNA by AAV9 provides highly efficient knockdown of ubiquitously expressed GFP in mouse heart, but not liver.Adeno-associated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling.Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.AAV recombineering with single strand oligonucleotides.Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments.Deletion of the B-B' and C-C' regions of inverted terminal repeats reduces rAAV productivity but increases transgene expression Formation of AAV single stranded DNA genome from a circular plasmid in Saccharomyces cerevisiae Viral single-strand DNA induces p53-dependent apoptosis in human embryonic stem cells.Adeno-associated virus: a key to the human genome?Parvovirus infection-induced DNA damage response Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex Effectiveness of gene delivery systems for pluripotent and differentiated cells.Versatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors.The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses Roles of E4orf6 and VA I RNA in adenovirus-mediated stimulation of human parvovirus B19 DNA replication and structural gene expression.Identification and Validation of Small Molecules That Enhance Recombinant Adeno-associated Virus Transduction following High-Throughput Screens.Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction E4Orf6-E1B-55k-dependent degradation of de novo-generated adeno-associated virus type 5 Rep52 and capsid proteins employs a cullin 5-containing E3 ligase complex.Parvovirus diversity and DNA damage responses Genetic manipulation of myoblasts and a novel primary myosatellite cell culture system: comparing and optimizing approaches.DNA damage promotes herpes simplex virus-1 protein expression in a neuroblastoma cell line.Recombinant adeno-associated viral vectors are deficient in provoking a DNA damage response.Identification of cellular proteins that interact with the adeno-associated virus rep protein Infectious molecular clones of adeno-associated virus isolated directly from human tissues.Viral and Cellular Components of AAV2 Replication Compartments.Viral manipulation of DNA repair and cell cycle checkpoints Induction of a Cellular DNA Damage Response by Porcine Circovirus Type 2 Facilitates Viral Replication and Mediates Apoptotic Responses.Adenovirus degradation of cellular proteins.Design stars: how small DNA viruses remodel the host nucleus.High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k "Helper" Proteins Cellular transduction mechanisms of adeno-associated viral vectors.Induced pluripotent stem cell clones reprogrammed via recombinant adeno-associated virus-mediated transduction contain integrated vector sequences.High-Density Recombinant Adeno-Associated Viral Particles are Competent Vectors for In Vivo Transduction.Bocavirus infection induces a DNA damage response that facilitates viral DNA replication and mediates cell death.

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P2860

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

http://www.wikidata.org/entity/Q40075782

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

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type

label

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

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prefLabel

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

@en

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P1433

Journal of Virology

P1476

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

@en

P2093

Geoffrey D Cassell

http://www.w3.org/2001/XMLSchema#string

Jose Alejandro Palacios

http://www.w3.org/2001/XMLSchema#string

Matthew D Weitzman

http://www.w3.org/2001/XMLSchema#string

Mauro Giacca

http://www.w3.org/2001/XMLSchema#string

Rachel A Schwartz

http://www.w3.org/2001/XMLSchema#string

Sarah Adam

http://www.w3.org/2001/XMLSchema#string

P2860

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus

Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue.

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

P304

12936-12945

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scholarly article

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10.1128/JVI.01523-07

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23

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81

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2007-09-26T00:00:00Z

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17898048

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2169118

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