Myc and human papillomavirus type 16 E7 genes cooperate to immortalize human keratinocytes.
about
ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cellsHuman papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylasesThe Asian-American E6 variant protein of human papillomavirus 16 alone is sufficient to promote immortalization, transformation, and migration of primary human foreskin keratinocytes.E6-associated protein (E6-AP) is a dual function coactivator of steroid hormone receptors.HPV E6 protein interacts physically and functionally with the cellular telomerase complex.Evidences suggesting involvement of viruses in oral squamous cell carcinoma.E6AP in the brain: one protein, dual function, multiple diseases.The human papillomavirus E7 oncoprotein as a regulator of transcription.The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1.Activation of telomerase by seminal plasma in malignant and normal cervical epithelial cells.HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function.TERT promoter hot spot mutations are frequent in Indian cervical and oral squamous cell carcinomas.Cell-restricted immortalization by human papillomavirus correlates with telomerase activation and engagement of the hTERT promoter by Myc.ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes.Direct HPV E6/Myc interactions induce histone modifications, Pol II phosphorylation, and hTERT promoter activation.
P2860
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P2860
Myc and human papillomavirus type 16 E7 genes cooperate to immortalize human keratinocytes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Myc and human papillomavirus t ...... mortalize human keratinocytes.
@en
type
label
Myc and human papillomavirus t ...... mortalize human keratinocytes.
@en
prefLabel
Myc and human papillomavirus t ...... mortalize human keratinocytes.
@en
P2093
P2860
P356
P1433
P1476
Myc and human papillomavirus t ...... mortalize human keratinocytes.
@en
P2093
Gary L Disbrow
Richard Schlegel
Vjekoslav Tomaic
Xuefeng Liu
P2860
P304
12689-12695
P356
10.1128/JVI.00669-07
P407
P577
2007-09-05T00:00:00Z