Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma.
about
Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MSComparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application.Sensitive Marker of the Cisplatin-DNA Interaction: X-Ray Photoelectron Spectroscopy of CL.Tuning heavy metal compounds for anti-tumor activity: is diversity the key to ruthenium's success?Capillary electrophoretic methods in the development of metal-based therapeutics and diagnostics: new methodology and applications.Anticancer metallodrug research analytically painting the "omics" picture--current developments and future trends.Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs.Electrophoretic separation techniques and their hyphenation to mass spectrometry in biological inorganic chemistry.Cobalt complexes as internal standards for capillary zone electrophoresis-mass spectrometry studies in biological inorganic chemistry.Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells.Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin.X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism.Maltol-derived ruthenium-cymene complexes with tumor inhibiting properties: the impact of ligand-metal bond stability on anticancer activity in vitro.In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands.The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes.Physicochemical Studies and Anticancer Potency of Ruthenium η-p-Cymene Complexes Containing Antibacterial QuinolonesCharacterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies.Metallomics for drug development: an integrated CE-ICP-MS and ICP-MS approach reveals the speciation changes for an investigational ruthenium(III) drug bound to holo-transferrin in simulated cancer cytosol.A shotgun metalloproteomic approach enables identification of proteins involved in the speciation of a ruthenium anticancer drug in the cytosol of cancer cells.Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development.
P2860
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P2860
Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Capillary electrophoresis hyph ...... ugs in human serum and plasma.
@en
type
label
Capillary electrophoresis hyph ...... ugs in human serum and plasma.
@en
prefLabel
Capillary electrophoresis hyph ...... ugs in human serum and plasma.
@en
P50
P356
P1433
P1476
Capillary electrophoresis hyph ...... ugs in human serum and plasma.
@en
P2093
Kasia Polec-Pawlak
P304
P356
10.1002/ELPS.200780790
P577
2008-05-01T00:00:00Z