Identification of a Prg4-expressing articular cartilage progenitor cell population in mice. - Wikidata - awgldk - TriplyDB

Identification of a Prg4-expressing articular cartilage progenitor cell population in mice.

Identification of a Prg4-expressing articular cartilage progenitor cell population in mice.

http://www.wikidata.org/entity/Q40095424

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Where is the common ground between bone marrow mesenchymal stem/stromal cells from different donors and species?Potential benefits and limitations of utilizing chondroprogenitors in cell-based cartilage therapy Articular Cartilage: Structural and Developmental Intricacies and Questions Spatial regulation of bone morphogenetic proteins (BMPs) in postnatal articular and growth plate cartilage Joint morphogenetic cells in the adult mammalian synovium Prg4-expressing cells: articular stem cells or differentiated progeny in the articular chondrocyte lineage?Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.Lubricin restoration in a mouse model of congenital deficiency.Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.Ageing and the pathogenesis of osteoarthritis.Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity.EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation Osteoarthritis: toward a comprehensive understanding of pathological mechanism.Confocal imaging of mouse mandibular condyle cartilage.Transcriptome-Wide Analyses of Human Neonatal Articular Cartilage and Human Mesenchymal Stem Cell-Derived Cartilage Provide a New Molecular Target for Evaluating Engineered Cartilage.Mesenchymal Stem/Progenitor Cells Derived from Articular Cartilage, Synovial Membrane and Synovial Fluid for Cartilage Regeneration: Current Status and Future Perspectives.Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs.Building and maintaining joints by exquisite local control of cell fate.Articular cartilage and joint development from embryogenesis to adulthood.Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB.Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis.Altered paracrine signaling from the injured knee joint impairs postnatal long bone growth Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes.Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.Human iPSC-derived chondrocytes mimic juvenile chondrocyte function for the dual advantage of increased proliferation and resistance to IL-1β.Inflammatory cytokines stabilize SOXC transcription factors to mediate the transformation of fibroblast-like synoviocytes in arthritic disease.Native joint-resident mesenchymal stem cells for cartilage repair in osteoarthritis.Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice.Tissue Force Programs Cell Fate and Tumor Aggression.Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo.Early genetic restoration of lubricin expression in transgenic mice mitigates chondrocyte peroxynitrite release and caspase-3 activation.Physioxia Promotes the Articular Chondrocyte-Like Phenotype in Human Chondroprogenitor-Derived Self-Organized Tissue.Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63.Regenerative medicine: Cartilage stem cells identified, but can they heal?A Joint Less Ordinary: Intriguing Roles for Hedgehog Signalling in the Development of the Temporomandibular Synovial Joint.Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis.Repair of Damaged Articular Cartilage: Current Approaches and Future Directions Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

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Identification of a Prg4-expressing articular cartilage progenitor cell population in mice.

http://www.wikidata.org/entity/Q40095424

description

2015 nî lūn-bûn

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Identification of a Prg4-expre ...... nitor cell population in mice.

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Identification of a Prg4-expre ...... nitor cell population in mice.

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Identification of a Prg4-expre ...... nitor cell population in mice.

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Arthritis & Rheumatology

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Identification of a Prg4-expre ...... nitor cell population in mice.

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Akio Kobayashi

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Andreia Ionescu

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Andrew B Lassar

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Elena Kozhemyakina

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Henry Kronenberg

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Matthew L Warman

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Minjie Zhang

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Noriaki Ono

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Ugur M Ayturk

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P2860

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome

The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth

BMP receptor signaling is required for postnatal maintenance of articular cartilage

Generalized lacZ expression with the ROSA26 Cre reporter strain

Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation

Foxa2 is required for the differentiation of pancreatic alpha-cells

Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

A global double-fluorescent Cre reporter mouse

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1261-1273

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10.1002/ART.39030

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5

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67

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4414823

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