Trastuzumab causes antibody-dependent cellular cytotoxicity-mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance.
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Changing strategies for target therapy in gastric cancerCurrent treatment of early breast cancer: adjuvant and neoadjuvant therapyThe strong in vivo anti-tumor effect of the UIC2 monoclonal antibody is the combined result of Pgp inhibition and antibody dependent cell-mediated cytotoxicityTwo novel human anti-ErbB2 immunoagents are active on trastuzumab-resistant tumours.The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.Immune Signatures Following Single Dose Trastuzumab Predict Pathologic Response to PreoperativeTrastuzumab and Chemotherapy in HER2-Positive Early Breast Cancer.HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.Trastuzumab emtansine: mechanisms of action and drug resistanceTrastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics.Emerging immunotherapeutics in adenocarcinomas: A focus on CAR-T cellsHer2/neu Expression in Wilms' Tumor and Correlation With Histopathologic Findings.A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy.Current status of anti-human epidermal growth factor receptor 2 therapies: predicting and overcoming herceptin resistanceA phase II trial of trastuzumab in combination with low-dose interleukin-2 (IL-2) in patients (PTS) with metastatic breast cancer (MBC) who have previously failed trastuzumab.Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells.Primary trastuzumab resistance: new tricks for an old drug.The emerging importance of α-L-fucose in human breast cancer: a review.Mild hyperthermia influence on Herceptin(®) properties.CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction.Trastuzumab-DM1 causes tumour growth inhibition by mitotic catastrophe in trastuzumab-resistant breast cancer cells in vivo.One target, different effects: a comparison of distinct therapeutic antibodies against the same targets.Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast CancerInhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant.Long-Term Partial Remission with Capecitabine/Trastuzumab in a Patient with Metastatic Breast Cancer Following Progression on Trastuzumab AloneSuperior antitumor activity of trastuzumab combined with capecitabine plus oxaliplatin in a human epidermal growth factor receptor 2-positive human gastric cancer xenograft model.Mechanisms of Resistance to Trastuzumab and Novel Therapeutic Strategies in HER2-Positive Breast CancerA common glycan structure on immunoglobulin G for enhancement of effector functionsTargeting HER2 Positive Breast Cancer with Chemopreventive Agents.Binding of trastuzumab to ErbB2 is inhibited by a high pericellular density of hyaluronan.Resistance to Trastuzumab in Breast Cancer.Understanding key assay parameters that affect measurements of trastuzumab-mediated ADCC against Her2 positive breast cancer cells.Is the Improved Efficacy of Trastuzumab and Lapatinib Combination Worth the Added Toxicity? A Discussion of Current Evidence, Recommendations, and Ethical Issues Regarding Dual HER2-Targeted Therapy.Targeting breast cancer stem cells with HER2-specific antibodies and natural killer cells.Is the skin a sanctuary for breast cancer cells during treatment with anti-HER2 antibodies?Development and Characterization of a Humanized Anti-HER2 Antibody HuA21 with Potent Anti-Tumor Properties in Breast Cancer Cells.The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancerThe combination of trastuzumab and pertuzumab administered at approved doses may delay development of trastuzumab resistance by additively enhancing antibody-dependent cell-mediated cytotoxicity.Models for prevention and treatment of cancer: problems vs promises.Predicting degree of benefit from adjuvant trastuzumab in NSABP trial B-31.Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D.
P2860
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P2860
Trastuzumab causes antibody-dependent cellular cytotoxicity-mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Trastuzumab causes antibody-de ...... ite intrinsic drug resistance.
@en
type
label
Trastuzumab causes antibody-de ...... ite intrinsic drug resistance.
@en
prefLabel
Trastuzumab causes antibody-de ...... ite intrinsic drug resistance.
@en
P2093
P921
P1476
Trastuzumab causes antibody-de ...... ite intrinsic drug resistance.
@en
P2093
Anita Kapanen
György Vereb
István Juhász
Jorma Isola
János Szöllösi
Minna Tanner
Márk Barok
Päivikki Kauraniemi
Zsuzsanna Pályi-Krekk
P304
P356
10.1158/1535-7163.MCT-06-0766
P50
P577
2007-07-01T00:00:00Z