Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs.
about
Unique bell-shaped voltage-dependent modulation of Na+ channel gating by novel insect-selective toxins from the spider Agelena orientalisState-dependent trapping of flecainide in the cardiac sodium channelStructural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugsStructural Basis for Pharmacology of Voltage-Gated Sodium and Calcium ChannelsEffects of pinacidil on guinea-pig isolated perfused heart with particular reference to the proarrhythmic effectThe mechanism of action of calcium antagonists on arrhythmias in early myocardial ischaemia: studies with nifedipine and DHM9Comprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependenceGlobal Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to painA computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythmsState-dependent compound inhibition of Nav1.2 sodium channels using the FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents.Effects of N-n-butyl haloperidol iodide on L-type calcium channels and intracellular free calcium in rat ventricular myocytes.Electromechanical and atrial and ventricular antiarrhythmic actions of CIJ-3-2F, a novel benzyl-furoquinoline vasodilator in rat heart.Kinetic analysis of phasic inhibition of neuronal sodium currents by lidocaine and bupivacainePosition of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.Use-dependent block of single sodium channels by lidocaine in guinea pig ventricular myocytes.Pharmacology and Toxicology of Nav1.5-Class 1 anti-arrhythmic drugs.Analysis of the action of lidocaine on insect sodium channels.The electrophysiological effects of antiarrhythmic potential of a secoaporphine, N-allylsecoboldine.The electrophysiological effects of dicentrine on the conduction system of rabbit heart.Electrophysiological effects of SD-3212, a new antiarrhythmic agent with vasodilator action, on guinea-pig ventricular cells.Cardiotoxic effects of fenfluramine hydrochloride on isolated cardiac preparations and ventricular myocytes of guinea-pigs.Barnidipine block of L-type Ca(2+) channel currents in rat ventricular cardiomyocytes.Evaluating state dependence and subtype selectivity of calcium channel modulators in automated electrophysiology assays.Inhibition of myocardial Ca2+ channels by three dihydropyridines with different structural features: potential-dependent blockade by Ro 18-3981.Resting, and rate-dependent depression of Vmax of guinea-pig ventricular action potentials by amiodarone and desethylamiodaroneQuinidine blocks cardiac sodium channels during opening and slow inactivation in guinea-pig papillary muscle.Electrophysiological effects of melperone on isolated rabbit heart muscles.Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle.Electrophysiological effects of OPC-88117, a new antiarrhythmic agent on papillary muscles and single ventricular myocytes isolated from guinea-pig heartsDifferent time courses of the blockade of sodium current by lignocaine and SUN 1165 in single myocytes isolated from guinea-pig atrium.Electrophysiological effects of diprafenone, a dimethyl congener of propafenone on guinea-pig ventricular cells.Electrophysiological effects of CRE-1087 in guinea-pig ventricular muscles.Fenoverine inhibition of calcium channel currents in single smooth muscle cells from rat portal vein and myometrium.Electrophysiological effects of the combination of mexiletine and flecainide in guinea-pig ventricular fibres.Effects of the two enantiomers, S-16257-2 and S-16260-2, of a new bradycardic agent on guinea-pig isolated cardiac preparations.Electrophysiological basis for antiarrhythmic efficacy, positive inotropy and low proarrhythmic potential of (-)-caryachine.The combined electrophysiological effects of lignocaine and sotalol in canine isolated cardiac Purkinje fibres are rate-dependentElectrophysiological effects of AFD-21 and AFD-19, new antiarrhythmic compounds on papillary muscles and single ventricular myocytes isolated from guinea-pig hearts.Effects of propafenone on calcium currents in single ventricular myocytes of guinea-pig.Nonmodal gating of cardiac calcium channels as revealed by dihydropyridines
P2860
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P2860
Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh
1984年學術文章
@zh-hant
name
Antiarrhythmic agents: the mod ...... alcium channel-blocking drugs.
@en
type
label
Antiarrhythmic agents: the mod ...... alcium channel-blocking drugs.
@en
prefLabel
Antiarrhythmic agents: the mod ...... alcium channel-blocking drugs.
@en
P1476
Antiarrhythmic agents: the mod ...... alcium channel-blocking drugs.
@en
P2093
Hondeghem LM
Katzung BG
P304
P356
10.1146/ANNUREV.PA.24.040184.002131
P577
1984-01-01T00:00:00Z