about
Ethanol prevents development of destructive arthritisCollagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cellsDestructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro.Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagenThe crystal structure of the pathogenic collagen type II-specific mouse monoclonal antibody CIIC1 Fab: structure to function analysisStructure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritisCrystal structure of an arthritogenic anticollagen immune complexEpitope-specific antibody response is controlled by immunoglobulin V H polymorphismsRelapsing polychondritis, induced in mice with matrilin 1, is an antibody- and complement-dependent diseaseA recombinant vaccine effectively induces c5a-specific neutralizing antibodies and prevents arthritisTwo monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry.Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice.Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis.Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity.Therapeutic cleavage of IgG: new avenues for treating inflammation.The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders.Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis.Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells.An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes.Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice.Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice.A single functional group substitution in c5a breaks B cell and T cell tolerance and protects against experimental arthritis.The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritisAdjuvant properties of a biocompatible thermo-responsive polymer of N-isopropylacrylamide in autoimmunity and arthritis.Collagen type II and a thermo-responsive polymer of N-isopropylacrylamide induce arthritis independent of Toll-like receptors: a strong influence by major histocompatibility complex class II and Ncf1 genes.Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis.Modulation of granulocyte-endothelium interactions by antileukoproteinase: inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium.Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases.Cartilage oligomeric matrix protein specific antibodies are pathogenicAntibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis.Dominant suppression of inflammation by glycan-hydrolyzed IgGThe role of collagen antibodies in mediating arthritis.Pathogenic antibody recognition of cartilage.Antibodies to citrullinated proteins: molecular interactions and arthritogenicity.Inhibiting the C5-C5a receptor axis.Reactive oxygen species in psoriasis and psoriasis arthritis: relevance to human disease.System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis.Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Kutty Selva Nandakumar
@ast
Kutty Selva Nandakumar
@en
Kutty Selva Nandakumar
@es
Kutty Selva Nandakumar
@sl
type
label
Kutty Selva Nandakumar
@ast
Kutty Selva Nandakumar
@en
Kutty Selva Nandakumar
@es
Kutty Selva Nandakumar
@sl
altLabel
Nan
@en
prefLabel
Kutty Selva Nandakumar
@ast
Kutty Selva Nandakumar
@en
Kutty Selva Nandakumar
@es
Kutty Selva Nandakumar
@sl
P1053
D-5438-2011
P106
P1153
35564710600
P1960
hgd4sGQAAAAJ
P2038
Kutty_Selva_Nandakumar
P21
P2798
P31
P496
0000-0001-7790-8197
P569
2000-01-01T00:00:00Z