Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization.
about
Adenosine A(1) receptor agonist N(6)-cyclohexyl-adenosine induced phosphorylation of delta opioid receptor and desensitization of its signaling.C-terminus of OX2R significantly affects downstream signaling pathwaysOpioid-receptor-heteromer-specific trafficking and pharmacology.β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons.Opioid receptor desensitization: mechanisms and its link to toleranceßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands.δ-Opioid mechanisms for ADL5747 and ADL5859 effects in mice: analgesia, locomotion, and receptor internalization.Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor FunctionChronic inflammatory injury results in increased coupling of delta opioid receptors to voltage-gated Ca2+ channels.Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences.Molecular Pharmacology of δ-Opioid Receptors.Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and β-arrestin 1 pathway.Modulation of opioid receptor function by protein-protein interactions.Ligand- and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists.Regulation of opioid receptor signalling: implications for the development of analgesic tolerance.An update of novel screening methods for GPCR in drug discovery.The delta opioid receptor tool box.In vivo techniques to investigate the internalization profile of opioid receptors.
P2860
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P2860
Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Phosphorylation of the delta-o ...... nylyl cyclase desensitization.
@en
type
label
Phosphorylation of the delta-o ...... nylyl cyclase desensitization.
@en
prefLabel
Phosphorylation of the delta-o ...... nylyl cyclase desensitization.
@en
P2860
P356
P1476
Phosphorylation of the delta-o ...... nylyl cyclase desensitization.
@en
P2093
P2860
P304
22315-22323
P356
10.1074/JBC.M611258200
P407
P50
P577
2007-06-12T00:00:00Z