Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability.
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Switching Akt: from survival signaling to deadly responseModulation of intracellular ROS levels by TIGAR controls autophagyRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesA new view of carcinogenesis and an alternative approach to cancer therapyReactive oxygen species in cancer stem cellsThe role of tumor suppressor p53 in the antioxidant defense and metabolismJanus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domainsIdentification of Sestrin3 Involved in the In vitro Resistance of Colorectal Cancer Cells to IrinotecanNR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotectionDifferent oxidative stress response in keratinocytes and fibroblasts of reconstructed skin exposed to non extreme daily-ultraviolet radiationUpregulation of sestrins protect atriums against oxidative damage and fibrosis in human and experimental atrial fibrillation.Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomasDifferential gene expression in patients with amyotrophic lateral sclerosis.Sestrins orchestrate cellular metabolism to attenuate aging.Microarray analysis of differential gene expression profile in peripheral blood cells of patients with human essential hypertension.Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformationRegulatory effects of sestrin 3 (SESN3) in BCR-ABL expressing cellsInsulin Increases Sestrin 2 Content by Reducing Its Degradation through the PI 3 K/mTOR Signaling Pathway.Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient miceChronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae.Sestrin2 expression is a favorable prognostic factor in patients with non-small cell lung cancer.Versatile functions of p53 protein in multicellular organismsFree radicals and senescence.Homeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense.Redox regulation of cell survivalOxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivativesCell cycle analysis of fetal germ cells during sex differentiation in mice.Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle.Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signalingStressin' Sestrins take an aging fight.Antioxidant and anti-proliferative properties of lycopene.Delivery to mitochondria: a narrower approach for broader therapeutics.Molecular pathways: reactive oxygen species homeostasis in cancer cells and implications for cancer therapy.EGFR signaling and autophagy dependence for growth, survival, and therapy resistance.Biochemical Basis of Sestrin Physiological Activities.Molecular mechanisms of mTOR regulation by stressTumor promotion by γ and suppression by β non-muscle actin isoforms.Ras-induced ROS upregulation affecting cell proliferation is connected with cell type-specific alterations of HSF1/SESN3/p21Cip1/WAF1 pathways.Ras activity levels control the development of pancreatic diseases.Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.
P2860
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P2860
Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Repression of sestrin family g ...... ation and genetic instability.
@en
type
label
Repression of sestrin family g ...... ation and genetic instability.
@en
prefLabel
Repression of sestrin family g ...... ation and genetic instability.
@en
P2093
P2860
P1433
P1476
Repression of sestrin family g ...... ation and genetic instability.
@en
P2093
Boris P Kopnin
Larissa S Agapova
Pavel B Kopnin
Peter M Chumakov
P2860
P304
P356
10.1158/0008-5472.CAN-06-2466
P407
P577
2007-05-01T00:00:00Z