Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1. - Wikidata - awgldk - TriplyDB

Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1.

Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1.

http://www.wikidata.org/entity/Q40140332

about

Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance Downstream gene activation of the receptor ALX by the agonist annexin A1.The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors.Phase II trial of the histone deacetylase inhibitor romidepsin in patients with recurrent/metastatic head and neck cancer Analysis of protein expression profiles in the thymus of chickens infected with Marek's disease virus.Epigenetic targets in hematological malignancies: combination therapies with HDACis and demethylating agents.Post-translational modifications of Runx1 regulate its activity in the cell Recent advances in the development of polyamine analogues as antitumor agents.Design of polyamine-based therapeutic agents: new targets and new directions CD72 regulates the growth of KIT-mutated leukemia cell line Kasumi-1.Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect.AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches.Chromosomal aberrations and fusion genes in myeloid malignancies.SIAH proteins: critical roles in leukemogenesis.Chromatin remodeling by polyamines and polyamine analogs.Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria.MicroRNA-196a promotes an oncogenic effect in head and neck cancer cells by suppressing annexin A1 and enhancing radioresistance.Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors.Strong Correlation between the Expression Levels of HDAC4 and SIRT6 in Hematological Malignancies of the Adults.Use of polyamine derivatives as selective histone deacetylase inhibitors.Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase.Polyamine-based small molecule epigenetic modulators.Acute myeloid leukemia with the t(8;21) translocation: clinical consequences and biological implications.The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1.Knockdown of Annexin A1 Enhances Radioresistance and Inhibits Apoptosis in Nasopharyngeal Carcinoma.

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P2860

Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1.

http://www.wikidata.org/entity/Q40140332

description

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2007年論文

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Novel role of HDAC inhibitors ...... rough induction of annexin A1.

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Novel role of HDAC inhibitors ...... rough induction of annexin A1.

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Novel role of HDAC inhibitors ...... rough induction of annexin A1.

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Cell Death & Differentiation

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Novel role of HDAC inhibitors ...... rough induction of annexin A1.

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P2860

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

The language of covalent histone modifications

Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation

Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies.

Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein.

Functional significance of histone deacetylase diversity.

Annexin I is an endogenous ligand that mediates apoptotic cell engulfment.

Annexin A1 down-regulation in head and neck cancer is associated with epithelial differentiation status.

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