P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.
about
The role of p21-activated kinases in hepatocellular carcinoma metastasisLKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domainP21-activated kinase-2 is a critical mediator of transforming growth factor-β-induced hepatoma cell migrationChemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cellsPAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics.Integrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma.Gbetagamma signaling promotes breast cancer cell migration and invasion.p21-Activated kinase-1 promotes aggressive phenotype, cell proliferation, and invasion in gestational trophoblastic disease.CDK5RAP3 is a novel repressor of p14ARF in hepatocellular carcinoma cells.Republished: tracing PAKs from GI inflammation to cancerA chemical genomic study identifying diversity in cell migration signaling in cancer cells.Reduced expression of p21-activated protein kinase 1 correlates with poor histological differentiation in pancreatic cancer.IPA-3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF-κB activation.Novel role for epidermal growth factor-like domain 7 in metastasis of human hepatocellular carcinoma.Prognostic importance and therapeutic implications of PAK1, a drugable protein kinase, in gastroesophageal junction adenocarcinoma.PAK1 as a therapeutic target.Contra-regulation of calcium- and integrin-binding protein 1-induced cell migration on fibronectin by PAK1 and MAP kinase signalingDysregulation of PAK1 Is Associated with DNA Damage and Is of Prognostic Importance in Primary Esophageal Small Cell Carcinoma.PAK1 is a therapeutic target in acute myeloid leukemia and myelodysplastic syndrome.Tyrosyl phosphorylated serine-threonine kinase PAK1 is a novel regulator of prolactin-dependent breast cancer cell motility and invasion.PAK1 and CtBP1 Regulate the Coupling of Neuronal Activity to Muscle Chromatin and Gene Expression.Onco-Golgi: Is Fragmentation a Gate to Cancer Progression?Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration.Pak protein kinases and their role in cancer.Growth hormone-releasing hormone receptor antagonists inhibit human gastric cancer through downregulation of PAK1-STAT3/NF-κB signalingPAK signaling in cancer.Tracing PAKs from GI inflammation to cancer.Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression.Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats.The tumor suppressor, TAX1BP2, is a novel substrate of ATM kinase.Multitargeting and antimetastatic potentials of silibinin in human HepG-2 and PLC/PRF/5 hepatoma cells.Paxillin phosphorylation by JNK and p38 is required for NFAT activation.Inhibition of JNK1 expression decreases migration and invasion of mouse hepatocellular carcinoma cell line in vitro.P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine.JNK-mediated phosphorylation of paxillin in adhesion assembly and tension-induced cell death by the adenovirus death factor E4orf4.A Novel Pak1/ATF2/miR-132 Signaling Axis Is Involved in the Hematogenous Metastasis of Gastric Cancer Cells.Peroxisome proliferator-activated receptor gamma ligand-mediated apoptosis of hepatocellular carcinoma cells depends upon modulation of PI3Kinase pathway independent of Akt.p21-activated kinases in Erbb2-positive breast cancer: A new therapeutic target?Role of C-Jun N-terminal Kinase in Hepatocellular Carcinoma Development.MAP4K4 promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma.
P2860
Q27016620-5BD9FF2B-980A-49E3-98CB-12755D4905ABQ28280001-348ACCF6-CBB9-44D2-9E06-0B9C1B2412CCQ28285920-7C7BEF0E-2E8F-4705-BFDA-4A679DCECD1BQ28538724-E65966C0-C954-4FAB-BF19-0DE3736C635AQ30488492-7D80BA6E-3AD8-4618-91E3-4A0799FDDD7CQ33828741-0BC58BB9-79B4-4679-9043-CD21D1FA5D37Q33861932-59E714B0-9F4E-4598-98DD-3A8B270C20BFQ33882580-29C234F2-D563-4DD3-945F-536E443BD3F3Q34364651-22376B86-7640-4101-B804-B170BCBF3BDBQ34463139-42DA4A4E-8F40-482E-8430-93080FB9AA93Q34472225-C83310AA-CFFE-44F8-BC36-4DF55ED66782Q34566032-C97D26EB-B395-4945-A895-A0B0D382D534Q34873314-9D432715-F712-489F-95B9-29963604A3F5Q35007692-0008E529-D1F1-465C-A6FE-3F2021ECCF68Q35043996-D816F00A-7E3E-4CCE-B94B-2C0033893A2CQ35108164-D48281F3-339A-4FEB-BC19-C2A773E4181AQ35387591-4094A85D-AB8A-431D-AD52-EB1215469EBBQ35813748-656D27DE-89C1-48A5-840B-37BFC757D6B6Q36000867-1F48DEFA-0D94-46EA-90CB-435A11D04F62Q36078608-1BE8191B-BD03-4311-977C-E577838A91B8Q36289547-58465A47-7AD5-49AD-89F2-F9D08BF0BDDFQ36776494-2F85F965-80DD-484E-867A-58736EECEF78Q37323621-F2F289AF-61F8-4A71-8BB2-48B458A4F3D7Q37376062-A0BDD874-A9BB-481A-8B4E-80B2F5366EEEQ37534187-692C0B93-ACC2-4A5F-8DC5-12642334E831Q38060732-C6054AD7-FCB2-47BC-BEC5-85C0EEED294FQ38210506-FC259271-0417-444E-9EBC-FE94FA53BB66Q38261073-752D943C-02F3-455F-9F89-E04E9D1F7DC5Q38937779-11562F01-F228-4525-860E-1D0F619D5439Q39062382-0EC84D24-1854-4EDE-8F2A-02AB76865B0EQ39154317-F650B6BD-8943-4412-9B78-D39D5062B996Q39302141-E20F9BFD-5B38-4B50-B0C1-7760B47F76E3Q39701679-DAA79C78-8305-4A87-821E-99BE32BEDD4BQ39828329-8DC3388E-0670-401A-8BD1-D9BA19A9E4FEQ39935651-764E0997-9A19-485A-862D-55C97F79631AQ41191006-BD7298BB-3257-4B9E-85FB-203D4D952C94Q41468565-70F8735A-33AE-4C68-88A2-7ECE3FBB416DQ42760698-FCE28C0E-AA60-4464-911C-85565D42642FQ51653926-210A3F8A-6A57-4957-9928-D016FAD91672Q53138552-8038EF0A-9F3E-41EE-9E5F-2378DF02E71E
P2860
P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
P21-activated protein kinase i ...... and paxillin phosphorylation.
@en
type
label
P21-activated protein kinase i ...... and paxillin phosphorylation.
@en
prefLabel
P21-activated protein kinase i ...... and paxillin phosphorylation.
@en
P2093
P1433
P1476
P21-activated protein kinase i ...... n and paxillin phosphorylation
@en
P2093
Dong-Yan Jin
Hai-Tao Xu
Man-Fong Lee
Veronica Y L Leong
Yick-Pang Ching
P304
P356
10.1158/0008-5472.CAN-06-3994
P407
P50
P577
2007-04-01T00:00:00Z