Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia. - Wikidata - awgldk - TriplyDB

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

http://www.wikidata.org/entity/Q40145557

about

PIAS1 interacts with FLASH and enhances its co-activation of c-Myb A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability New tricks from an old oncogene: gene fusion and copy number alterations of MYB in human cancer Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine Transcriptional network control of normal and leukaemic haematopoiesis Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1 Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis PHF6 mutations in T-cell acute lymphoblastic leukemia The landscape of somatic copy-number alteration across human cancers.c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells c-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xL Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis Comparative analysis of methods for identifying somatic copy number alterations from deep sequencing data.Frequent activation of EGFR in advanced chordomas.Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms.Array CGH in human leukemia: from somatics to genetics.Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults.c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.Fragile genomic sites are associated with origins of replication.The chicken miR-150 targets the avian orthologue of the functional zebrafish MYB 3'UTR target site.An integrated analysis of molecular aberrations in NCI-60 cell lines.Global genomic characterization of acute lymphoblastic leukemia microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma.Gene expression profiling of murine T-cell lymphoblastic lymphoma identifies deregulation of S-phase initiating genes.Transient responses to NOTCH and TLX1/HOX11 inhibition in T-cell acute lymphoblastic leukemia/lymphoma Pediatric low-grade gliomas: how modern biology reshapes the clinical field.Single molecule analysis of c-myb alternative splicing reveals novel classifiers for precursor B-ALL.Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines.Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia.Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia MYB expression and translocation in adenoid cystic carcinomas and other salivary gland tumors with clinicopathologic correlation.c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.

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P2860

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

http://www.wikidata.org/entity/Q40145557

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2007 nî lūn-bûn

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

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Barbara Cauwelier

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Carlos Graux

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Frederic Lambert

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Guy Froyen

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H Berna Beverloo

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Idoya Lahortiga

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Iwona Wlodarska

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Jules P P Meijerink

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Maria D Odero

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Marijke Bauters

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10.1038/NG2025

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5

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39

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Pieter Van Vlierberghe

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Kim De Keersmaecker

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