Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors.
about
Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice3' end mRNA processing: molecular mechanisms and implications for health and diseaseProgresses towards safe and efficient gene therapy vectorsFoamy virus vectors for HIV gene therapyDaedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectorsCross- and Co-Packaging of Retroviral RNAs and Their ConsequencesInsertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors.Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.Use of the piggyBac transposon to create stable packaging cell lines for the production of clinical-grade self-inactivating γ-retroviral vectors.Translating Sleeping Beauty transposition into cellular therapies: victories and challenges.Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleasesScale-up and manufacturing of clinical-grade self-inactivating γ-retroviral vectors by transient transfectionGammaretroviral vectors: biology, technology and applicationGraded or threshold response of the tet-controlled gene expression: all depends on the concentration of the transactivator.Influence of untranslated regions on retroviral mRNA transfer and expressionImproving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.Avoiding cytotoxicity of transposases by dose-controlled mRNA deliveryEvaluation of γ-retroviral vectors that mediate the inducible expression of IL-12 for clinical application.Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less-differentiated cells.Translation termination efficiency modulates ATF4 response by regulating ATF4 mRNA translation at 5' short ORFsEvading the immune response upon in vivo gene therapy with viral vectors.The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapyRecent advances in gene therapy for severe congenital immunodeficiency diseasesDevelopment of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognitionViral vectors: from virology to transgene expressionEnrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy.Integration-deficient lentiviral vectors: a slow coming of age.Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neuronsInclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human RetinaThe use of chromatin insulators to improve the expression and safety of integrating gene transfer vectorsBiosafety features of lentiviral vectorsA self-deletion lentiviral vector to reduce the risk of replication-competent virus formation.Viral expression cassette elements to enhance transgene target specificity and expression in gene therapy.Viral Vectors: The Road to Reducing Genotoxicity.Single-step cloning-screening method: a new tool for developing and studying high-titer viral vector producer cells.Going non-viral: the Sleeping Beauty transposon system breaks on through to the clinical side.Neonatal gene therapy of glycogen storage disease type Ia using a feline immunodeficiency virus-based vector.Cross-packaging of genetically distinct mouse and primate retroviral RNAs.Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery.
P2860
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P2860
Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Improving transcriptional term ...... oviral and lentiviral vectors.
@en
type
label
Improving transcriptional term ...... oviral and lentiviral vectors.
@en
prefLabel
Improving transcriptional term ...... oviral and lentiviral vectors.
@en
P2093
P356
P1433
P1476
Improving transcriptional term ...... oviral and lentiviral vectors.
@en
P2093
Christopher Baum
Melanie Galla
Rainer Loew
Tobias Maetzig
P304
P356
10.1038/SJ.MT.6300152
P577
2007-04-03T00:00:00Z