Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells.

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TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8 dependence.Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells.

P2860

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Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells.

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http://www.wikidata.org/entity/Q40151758

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2017 nî lūn-bûn

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2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

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2017年論文

@zh-tw

2017年论文

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2017年论文

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2017年论文

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Critical biological parameters ...... eceptor gene-modified T-cells.

@en

type

Item

label

Critical biological parameters ...... eceptor gene-modified T-cells.

@en

prefLabel

Critical biological parameters ...... eceptor gene-modified T-cells.

@en

P1476

Critical biological parameters ...... eceptor gene-modified T-cells.

@en

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Brian M Baker

http://www.w3.org/2001/XMLSchema#string

David C Murray

http://www.w3.org/2001/XMLSchema#string

Elizabeth Garrett-Mayer

http://www.w3.org/2001/XMLSchema#string

Gina M Scurti

http://www.w3.org/2001/XMLSchema#string

Kendra C Foley

http://www.w3.org/2001/XMLSchema#string

Lance M Hellman

http://www.w3.org/2001/XMLSchema#string

Michael I Nishimura

http://www.w3.org/2001/XMLSchema#string

Patricia E Simms

http://www.w3.org/2001/XMLSchema#string

Timothy T Spear

http://www.w3.org/2001/XMLSchema#string

Yuan Wang

http://www.w3.org/2001/XMLSchema#string

P2860

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Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex

Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor

Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response

Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination

Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity

Transforming binding affinities from three dimensions to two with application to cadherin clustering.

In vitro evolution of a T cell receptor with high affinity for peptide/MHC.

High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.

P2888

s00262-017-2032-9

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scholarly article

P356

10.1007/S00262-017-2032-9

http://www.w3.org/2001/XMLSchema#string

P577

2017-06-20T00:00:00Z

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1086103370

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P698

28634816

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P932

5647210

http://www.w3.org/2001/XMLSchema#string

Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells.

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P2860

P2860

Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells.

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P1433

P1476

P2093

P2860

P2888

P31

P356

P577

P6179

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P31

P356

P577

P6179

P698

P932