Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
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Role of exosomes/microvesicles in the nervous system and use in emerging therapiesExosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)The novel sorting nexin SNX33 interferes with cellular PrP formation by modulation of PrP sheddingSmall RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cellsIs tau ready for admission to the prion club?Extracellular Vesicles and a Novel Form of Communication in the BrainFocus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's DiseaseFocus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane VesiclesExosomes as Novel Regulators of Adult Neurogenic NichesmiRNAs: biological and clinical determinants in epilepsyExosomes as mediators of neuroinflammationProtease resistant protein cellular isoform (PrP(c)) as a biomarker: clues into the pathogenesis of HANDCellular aspects of prion replication in vitroExosomes: mediators of neurodegeneration, neuroprotection and therapeuticsInsight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profilingEmerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applicationsLegal but lethal: functional protein aggregation at the verge of toxicityThe complete exosome workflow solution: from isolation to characterization of RNA cargoExtracellular vesicles: exosomes, microvesicles, and friendsGetting a grip on prions: oligomers, amyloids, and pathological membrane interactions.Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy.Paracrine diffusion of PrP(C) and propagation of prion infectivity by plasma membrane-derived microvesiclesGlimepiride reduces the expression of PrPc, prevents PrPSc formation and protects against prion mediated neurotoxicity in cell lines.Infection of cell lines with experimental and natural ovine scrapie agents.Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion proteinInteraction and uptake of exosomes by ovarian cancer cells.Conservation of a glycine-rich region in the prion protein is required for uptake of prion infectivityA simple, versatile and sensitive cell-based assay for prions from various speciesGlycosylphosphatidylinositol anchor analogues sequester cholesterol and reduce prion formation.Spontaneous generation of mammalian prionsThe AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein.Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.First demonstration of transmissible spongiform encephalopathy-associated prion protein (PrPTSE) in extracellular vesicles from plasma of mice infected with mouse-adapted variant Creutzfeldt-Jakob disease by in vitro amplification.Neural stem cell-derived exosomes mediate viral entry.Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo.Neutron reflectometry studies define prion protein N-terminal peptide membrane bindingDifferential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patientsSequence-dependent internalization of aggregating peptidesThe neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes.
P2860
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P2860
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
@en
type
label
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
@en
prefLabel
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
@en
P50
P356
P1476
Packaging of prions into exosomes is associated with a novel pathway of PrP processing
@en
P2093
Masters CL
Sharples RA
P304
P356
10.1002/PATH.2145
P577
2007-04-01T00:00:00Z