The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
about
Genome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysisSWI/SNF chromatin remodeling complexes and cancerCyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer.Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene.Chromatin-regulating proteins as targets for cancer therapy.Brm inhibits the proliferative response of keratinocytes and corneal epithelial cells to ultraviolet radiation-induced damage.ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations.Complex alternative splicing of the smarca2 gene suggests the importance of smarca2-B variantsN-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells.Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians.SWI/SNF-Mediated Lineage Determination in Mesenchymal Stem Cells Confers Resistance to Osteoporosis.The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex.Hijacking the chromatin remodeling machinery: impact of SWI/SNF perturbations in cancer.Two BRM promoter insertion polymorphisms increase the risk of early-stage upper aerodigestive tract cancers.Chromatin regulators with tumor suppressor properties and their alterations in human cancers.Vulnerabilities of mutant SWI/SNF complexes in cancer.Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.Aberrant BAF57 signaling facilitates prometastatic phenotypes.Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin.Beyond Mutations: Additional Mechanisms and Implications of SWI/SNF Complex Inactivation.The absence of Brm exacerbates photocarcinogenesis.Driver mutations of cancer epigenomes.The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines.Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers.Association of two BRM promoter polymorphisms with head and neck squamous cell carcinoma risk.Pharmacologic reversal of epigenetic silencing of the anticancer protein BRM: a novel targeted treatment strategy.Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development.BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours.Association of a single-nucleotide polymorphism from chromosome 17q12 with the aggressiveness of prostate cancer in a Hispanic population.Two BRM promoter polymorphisms predict poor survival in patients with hepatocellular carcinoma.BRM/SMARCA2-negative clear cell renal cell carcinoma is associated with a high percentage of BRM somatic mutations, deletions and promoter methylation.
P2860
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P2860
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
@en
type
label
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
@en
prefLabel
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
@en
P2093
P2860
P50
P1433
P1476
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
@en
P2093
Ankur Sharma
Bernard Weissman
Christian Muchardt
Clay E S Comstock
Erin Williams
Gary Rosson
Katherine Weaver
Monica P Revelo
Moshe Yaniv
P2860
P304
10154-10162
P356
10.1158/0008-5472.CAN-08-1794
P407
P577
2008-12-01T00:00:00Z