Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.
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HNF4 alpha orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cellsImproved conditional expression systems resulting in physiological level of HNF4alpha expression confirm HNF4alpha induced apoptosis in the pancreatic beta-cell line INS-1.A unique four-hub protein cluster associates to glioblastoma progression.A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.Impairment of hepatic nuclear factor-4α binding to the Stim1 promoter contributes to high glucose-induced upregulation of STIM1 expression in glomerular mesangial cellsDevelopmental programming of neonatal pancreatic β-cells by a maternal low-protein diet in rats involves a switch from proliferation to differentiation.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cellsNuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation.Role of hepatocyte nuclear factor 4α (HNF4α) in cell proliferation and cancer.MicroRNAs regulate human hepatocyte nuclear factor 4alpha, modulating the expression of metabolic enzymes and cell cycle.Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents.
P2860
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P2860
Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Tissue-specific transcription ...... ncreatic INS-1 beta-cell line.
@en
type
label
Tissue-specific transcription ...... ncreatic INS-1 beta-cell line.
@en
prefLabel
Tissue-specific transcription ...... ncreatic INS-1 beta-cell line.
@en
P2093
P2860
P356
P1433
P1476
Tissue-specific transcription ...... ncreatic INS-1 beta-cell line.
@en
P2093
Belén Lucas
Gerhart U Ryffel
Heike Thomas
Jörn Lausen
Ludger Klein-Hitpass
Sabine Senkel
Silke Erdmann
Tanja Arndt
P2860
P304
P356
10.1515/BC.2007.011
P577
2007-01-01T00:00:00Z