Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand - Wikidata - awgldk - TriplyDB

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

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Identification of an endogenous ligand bound to a native orphan nuclear receptor Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans Mechanisms of gene regulation by fatty acids Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans Structural Basis of Natural Promoter Recognition by a Unique Nuclear Receptor, HNF4 : DIABETES GENE PRODUCT Structural Insights into Inhibition of Bacillus anthracis Sporulation by a Novel Class of Non-heme Globin Sensor Domains Multidomain integration in the structure of the HNF-4α nuclear receptor complex Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional state Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally Distinct Regulation of rat hepatic L-pyruvate kinase promoter composition and activity by glucose, n-3 polyunsaturated fatty acids, and peroxisome proliferator-activated receptor-alpha agonist Proteomic characterization of early changes induced by triiodothyronine in rat liver Signalling cross-talk between hepatocyte nuclear factor 4alpha and growth-hormone-activated STAT5b Thioesterase activity and acyl-CoA/fatty acid cross-talk of hepatocyte nuclear factor-4{alpha}Network insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: a review What are nuclear receptor ligands?The role of nuclear receptor NHR-64 in fat storage regulation in Caenorhabditis elegans Nuclear receptors: the evolution of diversity.Dynamic regulation of Drosophila nuclear receptor activity in vivo.Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.An amphioxus orthologue of the estrogen receptor that does not bind estradiol: insights into estrogen receptor evolution.The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1.A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49.Association of the CPT1B gene with skeletal muscle fat infiltration in Afro-Caribbean men.SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.Structural basis for HNF-4alpha activation by ligand and coactivator binding.HNF4α--role in drug metabolism and potential drug target?Structural and functional insights into nuclear receptor signaling.Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes Med25 is required for RNA polymerase II recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver.Hepatic hepatocyte nuclear factor 4α is essential for maintaining triglyceride and cholesterol homeostasis.Predicting inductive drug-drug interactions.Hepatocyte nuclear factor 4 alpha polymorphisms and the metabolic syndrome in French-Canadian youth Two functional modes of a nuclear receptor-recruited arginine methyltransferase in transcriptional activation.Upregulation of Scavenger Receptor BI by Hepatic Nuclear Factor 4α through a Peroxisome Proliferator-Activated Receptor γ-Dependent Mechanism in Liver.Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids

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Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

http://www.wikidata.org/entity/Q27639521

description

2002 nî lūn-bûn

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2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年学术文章

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Journal of Biological Chemistry

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Crystal structure of the HNF4 ...... h endogenous fatty acid ligand

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Karen Duda

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Melanie Iwamoto

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Steven E Shoelson

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Young-In Chi

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P2860

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

Determination of macromolecular structures from anomalous diffraction of synchrotron radiation

Detection, delineation, measurement and display of cavities in macromolecular structures

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1808391

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10.1074/JBC.C200420200

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41

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277

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12193589

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crystal structure