Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR.
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3D Structure of the Dihydropyridine Receptor of Skeletal MuscleCritical Role of Intracellular RyR1 Calcium Release Channels in Skeletal Muscle Function and DiseasePharmGKB summary: succinylcholine pathway, pharmacokinetics/pharmacodynamicsCa(V)1.1: The atypical prototypical voltage-gated Ca²⁺ channelPharmGKB summary: very important pharmacogene information for RYR1Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal RegionMinding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicityCalcium homeostasis in myogenic differentiation factor 1 (MyoD)-transformed, virally-transduced, skin-derived equine myotubesMyoplasmic resting Ca2+ regulation by ryanodine receptors is under the control of a novel Ca2+-binding region of the receptor.RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes.Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle.A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR.Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptorAblation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubesBasal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice.Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice.Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leakMalignant hyperthermia: a pharmacogenetic disorder.Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle.Maternal high-altitude hypoxia and suppression of ryanodine receptor-mediated Ca2+ sparks in fetal sheep pulmonary arterial myocytes.Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia.Halothane modulation of skeletal muscle ryanodine receptors: dependence on Ca2+, Mg2+, and ATP.Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene.The disorders of the calcium release unit of skeletal muscles: what have we learned from mouse models?Coupling of excitation to Ca2+ release is modulated by dysferlin.Genotype-Phenotype Correlations of Malignant Hyperthermia and Central Core Disease Mutations in the Central Region of the RYR1 Channel.Potassium dependent rescue of a myopathy with core-like structures in mouse.Functional analysis of RYR1 variants linked to malignant hyperthermia.Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations.Defects in Ca2+ release associated with local expression of pathological ryanodine receptors in mouse muscle fibres.
P2860
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P2860
Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Elevated resting [Ca(2+)](i) i ...... sive calcium leak from the SR.
@en
type
label
Elevated resting [Ca(2+)](i) i ...... sive calcium leak from the SR.
@en
prefLabel
Elevated resting [Ca(2+)](i) i ...... sive calcium leak from the SR.
@en
P2093
P2860
P1476
Elevated resting [Ca(2+)](i) i ...... sive calcium leak from the SR.
@en
P2093
Eric Esteve
Isaac N Pessah
José R López
Paul D Allen
Tadeusz F Molinski
Tianzhong Yang
P2860
P304
P356
10.1152/AJPCELL.00133.2006
P577
2006-12-20T00:00:00Z