Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein.
about
International Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsTargeting protein kinases in central nervous system disordersPhysicochemical selectivity of the BBB microenvironment governing passive diffusion--matching with a porcine brain lipid extract artificial membrane permeability model.Bilastine: in allergic rhinitis and urticaria.A new in situ brain perfusion flow correction method for lipophilic drugs based on the pH-dependent Crone-Renkin equation.Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.An open clinical trial on the efficacy of cetirizine hydrochloride in the management of allergic pruritus in cats.Improving the prediction of the brain disposition for orally administered drugs using BDDCS.First-trimester antihistamine exposure and risk of spontaneous abortion or preterm birth.P-glycoprotein deficient mouse in situ blood-brain barrier permeability and its prediction using an in combo PAMPA model.Drug interactions at the blood-brain barrier: fact or fantasy?Drug metabolism and pharmacokinetics.Gender and interindividual variability in pharmacokinetics.Safety and efficacy of bilastine: a new H(1)-antihistamine for the treatment of allergic rhinoconjunctivitis and urticaria.Full efficacy with no CNS side-effects: unachievable panacea or reality? DMPK considerations in design of drugs with limited brain penetration.Blood-brain barrier permeation and efflux exclusion of anticholinergics used in the treatment of overactive bladder.Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.Inhibitory effect of clemastine on P-glycoprotein expression and function: an in vitro and in situ studyFexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration.Predicting apparent passive permeability of Caco-2 and MDCK cell-monolayers: A mechanistic model.The role of P-glycoprotein in CNS antihistamine effects.
P2860
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P2860
Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Assessment of the first and se ...... on and role of P-glycoprotein.
@en
type
label
Assessment of the first and se ...... on and role of P-glycoprotein.
@en
prefLabel
Assessment of the first and se ...... on and role of P-glycoprotein.
@en
P2093
P2860
P1476
Assessment of the first and se ...... on and role of P-glycoprotein.
@en
P2093
Glenn G Dobson
Ismael J Hidalgo
Tanja Obradovic
Thomas Kungu
Tomotaka Shingaki
P2860
P304
P356
10.1007/S11095-006-9149-4
P577
2006-12-19T00:00:00Z